Quantitative imaging performance of frequency-tunable capacitive micromachined ultrasonic transducer array designed for intracardiac application: Phantom study

Pekař, Martin; Mihajlović, Nenad; Belt, H.J.W.; Kolen, Alexander F.; Rens, Jeannet van; Budzelaar, F. P. M.; Jacobs, B.; Bosch, Johan G.; Vos, Hendrik J.; Rem-Bronneberg, Debbie; Soest, Gijs van; Steen, Antonius F.W. van der

doi:10.1016/j.ultras.2017.11.021

Cited by 12 publications

(8 citation statements)

References 20 publications

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“…Furthermore, CMUTs are also CMOS-compatible and have small form factor [64]. Currently, three types of CMUTs have been reported for IVUS imaging applications: cylindrical CMUT array [65], phased CMUT array [66][67][68] Compared with conventional piezoelectric ultrasound transducers, PMUT demonstrates its uniqueness for IVUS imaging. Contrary to conventional piezoelectric ultrasound transducer, PMUT is compatible with complementary metal oxide semiconductor (CMOS), which means that the fabrication process of PMUT can be easily integrated with supporting electronic circuits.…”

Section: Ivus Cathetermentioning

confidence: 99%

“…Furthermore, CMUTs are also CMOS-compatible and have small form factor [64]. Currently, three types of CMUTs have been reported for IVUS imaging applications: cylindrical CMUT array [65], phased CMUT array [66][67][68] Due to the flexibility of the CMUT array, it could be wrapped around a 3 Fr catheter tip for side looking IVUS imaging. Xu et al [66] designed and fabricated four 12-element 1D CMUT phased arrays for cross-sectional imaging of artery.…”

Section: Ivus Cathetermentioning

confidence: 99%

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Recent Advances in Transducers for Intravascular Ultrasound (IVUS) Imaging

Peng

Kim

et al. 2021

Sensors

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As a well-known medical imaging methodology, intravascular ultrasound (IVUS) imaging plays a critical role in diagnosis, treatment guidance and post-treatment assessment of coronary artery diseases. By cannulating a miniature ultrasound transducer mounted catheter into an artery, the vessel lumen opening, vessel wall morphology and other associated blood and vessel properties can be precisely assessed in IVUS imaging. Ultrasound transducer, as the key component of an IVUS system, is critical in determining the IVUS imaging performance. In recent years, a wide range of achievements in ultrasound transducers have been reported for IVUS imaging applications. Herein, a comprehensive review is given on recent advances in ultrasound transducers for IVUS imaging. Firstly, a fundamental understanding of IVUS imaging principle, evaluation parameters and IVUS catheter are summarized. Secondly, three different types of ultrasound transducers (piezoelectric ultrasound transducer, piezoelectric micromachined ultrasound transducer and capacitive micromachined ultrasound transducer) for IVUS imaging are presented. Particularly, the recent advances in piezoelectric ultrasound transducer for IVUS imaging are extensively examined according to their different working mechanisms, configurations and materials adopted. Thirdly, IVUS-based multimodality intravascular imaging of atherosclerotic plaque is discussed. Finally, summary and perspectives on the future studies are highlighted for IVUS imaging applications.

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Section: Ivus Cathetermentioning

confidence: 99%

“…Furthermore, CMUTs are also CMOS-compatible and have small form factor [64]. Currently, three types of CMUTs have been reported for IVUS imaging applications: cylindrical CMUT array [65], phased CMUT array [66][67][68] Due to the flexibility of the CMUT array, it could be wrapped around a 3 Fr catheter tip for side looking IVUS imaging. Xu et al [66] designed and fabricated four 12-element 1D CMUT phased arrays for cross-sectional imaging of artery.…”

Section: Ivus Cathetermentioning

confidence: 99%

Recent Advances in Transducers for Intravascular Ultrasound (IVUS) Imaging

Peng

Kim

et al. 2021

Sensors

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“…13,14 Breakthroughs in capacitive micromachined ultrasound transducers enable the integration and miniaturization of ultrasound technology. 32,33 Integrated ultrasonic transducers could monitor the IVS position in real time for automatic pump speed adaptation. Our study utilized an ultrasound transducer equivalent to a probe with 156 individual transducers and would generate a large amount of data if used in real time.…”

Section: Discussionmentioning

confidence: 99%

Does Size Matter for Female Continuous-flow LVAD Recipients? A Translational Approach to a Decade Long Question

Dual

Nayak

et al. 2021

ASAIO Journal

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Females have increased risk of right-ventricular failure (RVF) and 3 month mortality after left-ventricular assist device (LVAD) implantation. In this translational study, we tested the hypothesis that sex differences in outcomes are driven by pump-induced LV size-volume mismatch, due to a negative impact on interventricular septal (IVS) interdependence. Adult continuous-flow LVAD recipients from the International Society For Heart And Lung Transplantation Mechanically Assisted Circulatory Support registry (n = 15,498) were studied to determine association of female sex with outcomes of 3 month mortality and RVF. Female sex was associated with smaller preimplant left-ventricular end-diastolic diameter (6.5 vs. 6.9 cm, p < 0.001), increased 3 month mortality (odds ratio [OR]: 1.42, p < 0.001) and RVF (OR: 1.18, p = 0.005). Smaller left-ventricular end-diastolic diameter was associated with worse outcomes after LVAD implantation (OR for mortality: 1.20, p < 0.001; RVF: 1.09, p < 0.001), and attenuated the association of female sex with these outcomes. In test bench heart phantoms (n = 4), the IVSs of smaller hearts demonstrated abnormal leftward shift earlier than larger hearts (volume change at IVS shift: 40 [95% confidence interval: 30–52] vs. 50 [95% confidence interval: 48–69] ml). Smaller LV size partially mediates worse post-LVAD outcomes for female patients, due to lower volume thresholds for adverse IVS shifting.

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“…The phased array can also satisfy the design requirements of forward-looking ICE and IVUS systems to provide overall and detailed imaging near the catheter probe. A catheter with these considerations was realized by Pekar et al 68 based on a 32-element frequency-tunable CMUTphased array (Fig. 5b).…”

Section: Phased Cmut Arraymentioning

confidence: 99%

Capacitive micromachined ultrasound transducers for intravascular ultrasound imaging

et al. 2020

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Intravascular ultrasound (IVUS) is a burgeoning imaging technology that provides vital information for the diagnosis of coronary arterial diseases. A significant constituent that enables the IVUS system to attain high-resolution images is the ultrasound transducer, which acts as both a transmitter that sends acoustic waves and a detector that receives the returning signals. Being the most mature form of ultrasound transducer available in the market, piezoelectric transducers have dominated the field of biomedical imaging. However, there are some drawbacks associated with using the traditional piezoelectric ultrasound transducers such as difficulties in the fabrication of high-density arrays, which would aid in the acceleration of the imaging speed and alleviate motion artifact. The advent of microelectromechanical system (MEMS) technology has brought about the development of micromachined ultrasound transducers that would help to address this issue. Apart from the advantage of being able to be fabricated into arrays with lesser complications, the image quality of IVUS can be further enhanced with the easy integration of micromachined ultrasound transducers with complementary metal-oxide-semiconductor (CMOS). This would aid in the mitigation of parasitic capacitance, thereby improving the signal-to-noise. Currently, there are two commonly investigated micromachined ultrasound transducers, piezoelectric micromachined ultrasound transducers (PMUTs) and capacitive micromachined ultrasound transducers (CMUTs). Currently, PMUTs face a significant challenge where the fabricated PMUTs do not function as per their design. Thus, CMUTs with different array configurations have been developed for IVUS. In this paper, the different ultrasound transducers, including conventional-piezoelectric transducers, PMUTs and CMUTs, are reviewed, and a summary of the recent progress of CMUTs for IVUS is presented.

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Quantitative imaging performance of frequency-tunable capacitive micromachined ultrasonic transducer array designed for intracardiac application: Phantom study

Cited by 12 publications

References 20 publications

Recent Advances in Transducers for Intravascular Ultrasound (IVUS) Imaging

Recent Advances in Transducers for Intravascular Ultrasound (IVUS) Imaging

Does Size Matter for Female Continuous-flow LVAD Recipients? A Translational Approach to a Decade Long Question

Capacitive micromachined ultrasound transducers for intravascular ultrasound imaging

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