Quantitative Measurement of Regional Blood Flow in Hepatic Focal Nodular Hyperplasia Findings on Positron Emission Tomography

Relationships between oxygen and glucose metabolism in human liver tumours: positron emission tomography using 15O and 18F-deoxyglucose

“…In addition, the results obtained from liver tumour quantification using PET images were parallel to the angiographic and dynamic CT results [16][17][18]. 18 FDG study that were already very complicated. Therefore, the C 15 O inhalation method [19] had to be omitted, and we adopted only Frackowiak's method without correction for blood volume.…”

“…Finally, a 185 MBq (5 mCi) bolus of 18 FDG was administered intravenously, and static scanning was performed for 6 min, 40 min later (Hawkins' level 2 study) [13]. Serum glucose was determined immediately before 18 FDG injection.…”

“…In contrast, the H 2 15 O dynamic method can measure r using non-linear multiple regression analysis for each tumour, as different hepatic tumours may require different values for this coefficient. Therefore, the dynamic method [16][17][18], rather than the steady-state method, was used for Ft. In addition, the results obtained from liver tumour quantification using PET images were parallel to the angiographic and dynamic CT results [16][17][18].…”

“…Therefore, the dynamic method [16][17][18], rather than the steady-state method, was used for Ft. In addition, the results obtained from liver tumour quantification using PET images were parallel to the angiographic and dynamic CT results [16][17][18]. 18 FDG study that were already very complicated.…”

“…This index has the advantage of technical simplicity, with no need for arterial blood sampling or complicated models. SUV, however, is dependent on body weight and the time difference between 18 FDG injection and image acquisition [20]. SUV should be measured after tumour 18 FDG uptake has reached a plateau, when the concentration of 18 FDG in the tumour no longer depends on 18 FDG transport variables.…”