2005
DOI: 10.1007/s00534-004-0936-1
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Spontaneous rupture and hemorrhage of hepatic focal nodular hyperplasia in lobus caudatus

Abstract: In general, focal nodular hyperplasia lesions of the liver have a benign natural course; the majority of cases remain asymptomatic and complications are rare. We report a case of spontaneous rupture and hemorrhage of focal nodular hyperplasia, which is extremely rare in the literature. A 35-year-old woman was admitted with severe upper abdominal pain and unstable hemodynamic status. No major abdominal trauma was noted. Radiology findings suggested a diffuse hemoperitoneum. Emergent surgical exploration showed … Show more

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Cited by 30 publications
(14 citation statements)
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“…33,34 Although FNH is traditionally associated with a very low to no incidence of complications, scattered reports suggest that complications of FNH such as rupture and bleeding do occur, although much less frequently than in the context of hepatic adenoma. [35][36][37][38][39] Albeit that the majority of patients with FNH are asymptomatic and are managed conservatively with observation, patients who develop abdominal pain, marked tumour enlargement or have atypical imaging findings may require surgery. 40,41 On follow-up, up to 13% of patients who are under surveillance for FNH go on to develop protracted symptoms.…”
Section: Discussionmentioning
confidence: 99%
“…33,34 Although FNH is traditionally associated with a very low to no incidence of complications, scattered reports suggest that complications of FNH such as rupture and bleeding do occur, although much less frequently than in the context of hepatic adenoma. [35][36][37][38][39] Albeit that the majority of patients with FNH are asymptomatic and are managed conservatively with observation, patients who develop abdominal pain, marked tumour enlargement or have atypical imaging findings may require surgery. 40,41 On follow-up, up to 13% of patients who are under surveillance for FNH go on to develop protracted symptoms.…”
Section: Discussionmentioning
confidence: 99%
“…En algunas oportunidades, la masa tumoral tiene otras ubicaciones; se describe un caso de s铆ndrome de Budd-Chiari por compresi贸n de venas hep谩ticas por la masa tumoral 5 . Tambi茅n se ha publicado un caso excepcional de ruptura y hemoperitoneo 6 . La presencia de una escara central, tanto en el hepatocarcinoma fibrolamelar como en la hiperplasia nodular focal, hicieron pensar que podr铆a ser una tumoraci贸n premaligna 7 .…”
Section: Discussionunclassified
“…It is based on pathological features that FNH is typically supplied by a single and hyperplastic artery with little arteriovenous shunting, which makes it an ideal target for TAE 33 . But, in spontaneous hemorrhagic FNH, as it tends to be larger and with more vascularity, TAE can result in temporary cessation of the hemorrhage, but bleeding may recur later, 26 so it could be an alternative as a life鈥恠aving hemostasis procedure before further investigations are undertaken to better define the nature and extent of the lesion and to carry out surgical removal 27 …”
Section: Discussionmentioning
confidence: 99%