Quantitative measurement of thyroid blood flow for differentiation of painless thyroiditis from Graves’ disease

Ota, Hisashi; Amino, Nobuyuki; Morita, Shinji; Kobayashi, Kaoru; Kubota, Sumihisa; Fukata, Shuji; Kamiyama, Naohisa; Miyauchi, Akira

doi:10.1111/j.1365-2265.2007.02832.x

Cited by 113 publications

(78 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Destructive thyrotoxicosis in patients with painless thyroiditis was carefully distinguished from Graves' hyperthyroidism [9]. Patients who were pregnant, within one year after delivery or lactating baby were excluded from this study.…”

Section: Resultsmentioning

confidence: 99%

Menstrual disturbances in various thyroid diseases

et al. 2010

Self Cite

View full text Add to dashboard Cite

IT has been reported that thyroid dysfunction is frequently associated with menstrual disturbances. Amenorrhea was one of the earlier known clinical changes associated with hyperthyroidism, as reported by von Basedow in 1840 [1]. Since then, amenorrhea has frequently been reported, along with a number of other changes in the menstrual cycle, including oligomenorrhea, hypomenorrhea and anovulation. These disturbances have been reported in more than half the patients with hyperthyroidism [2,3].On the other hands, hypermenorrhea and polymenorrhea have also been reported in about 50~80 % of patients with hypothyroidism [2-4]. These changes are sometimes related to ovulatory disturbance and subsequent infertility [5,6] and thus clinicians have focused on these problems for long time.However, these previous studies were performed in the 1950s and 1960s in a small number of patients with thyroid dysfunction. Abstract. The prevalence of menstrual disturbances, including secondary amenorrhea, hypomenorrhea, oligomenorrhea, hypermenorrhea, polymenorrhea and irregular menstrual cycle were prospectively examined in 586 patients with hyperthyroidism due to Graves' disease, 111 with hypothyroidism, 558 with euthyroid chronic thyroiditis, 202 with painless thyroiditis and 595 with thyroid tumor. In the overall patient group, the prevalence did not different from that in 105 healthy controls. However, patients with severe hyperthyroidism showed a higher prevalence of secondary amenorrhea (2.5%) and hypomenorrhea (3.7%) than those (0.2% and 0.9%, respectively) with mild or moderate hyperthyroidism. Moreover, patients with severe hypothyroidism had a higher prevalence (34.8%) of menstrual disturbances than mildmoderate cases (10.2%). Menstrual disturbances in thyroid dysfunction were less frequent than previously thought.

show abstract

Section: Resultsmentioning

confidence: 99%

Menstrual disturbances in various thyroid diseases

et al. 2010

Self Cite

View full text Add to dashboard Cite

show abstract

“…The operator effect is one of the drawbacks of ultrasonography. 26,27 In this study, the same examiner conducted all of the ultrasound measurements and image processing to avoid intertester bias. This examiner had excellent knowledge of anatomy and extensive training in using ultrasound to examine the foot.…”

Section: Discussionmentioning

confidence: 99%

Association Between Plantar Fascia Vascularity and Morphology and Foot Dysfunction in Individuals With Chronic Plantar Fasciitis

Chen¹,

Ho²,

Ying³

et al. 2013

Journal of Orthopaedic & Sports Physical Therapy

View full text Add to dashboard Cite

Plantar fasciitis is one of the most common painful foot con ditions. It affects both active and sedentary adults, with a peak incidence in those between 40 and 60 years of age. 8,20 Impaired vascularity with subsequent metabolic disturbance has been proposed as one of its causes.11,31 A moderate to marked increase in vascularity in the proximal plantar fascia has been observed in patients with plantar fasciitis. 7,31 This increase is typical in those who have had plantar fasciitis for less than 12 months, and has been associated with greater intensity of pain.31 Similar vascularization has been observed in patients with Achilles, 23,36 patellar, 9 and rotator cuff tendinopathy. 18 The intensity of pain with chronic tendinopathy has also been found to be greater in patients with tendon vascularization compared to those without. 9,10,38 Alfredson 2 proposed that vascularization in diseased tendons is one of the potential mediators of pain in tendinopathy, nerve ingrowth associated with new vessels being the cause of pain reported by patients.Higher tendon vascularity has also been reported to be associated with greater dysfunction in patients with patellar 9 and Achilles tendinopathy. T T METHODS:Thirty-eight patients with chronic unilateral plantar fasciitis and 21 controls participated in this study. Proximal plantar fascia vascularization and thickness were assessed using ultrasound imaging, and pain and foot dysfunction were quantified with a visual analog scale and the Chinese version of the Foot Function Index, respectively. Paired t tests were used to assess the side-to-side differences in fascia thickness and vascularity index (VI) in the control and patient groups, and an unpaired t test was used to make comparisons with the patient group. Multiple regression analysis was performed to identify whether the VI and fascia thickness were associated with pain and foot dysfunction. T T RESULTS:There were significantly higher VI (mean  SD, 2.4%  1.4%) and fascia thickness (5.0  1.3 mm) values in the affected feet when compared with the unaffected feet in the patient group (VI, 1.4%  0.5%; fascia thickness, 3.3  0.7 mm) and with the dominant side of the controls (VI, 1.6%  0.4%; fascia thickness, 2.9  0.6 mm). After accounting for age, gender, body mass index, and duration of symptoms, the VI explained 13% and 33% of the variance in pain scores measured with a visual analog scale and the pain subscale of the Foot Function Index, respectively; the VI and fascia thickness explained 42% of the variance in the Foot Function Index. T T CONCLUSION: Individuals with unilateralchronic plantar fasciitis demonstrated significantly greater vascularity and thickened fascia on the affected side compared to the unaffected side and also to healthy controls. Fascia vascularity was associated independently with self-perceived pain, and both fascia vascularity and thickness were associated with foot dysfunction in patients with chronic plantar fasciitis. Public trials registry: Current Controlled Trials, ISRCTN49594569. J...

show abstract

“…TBF was significantly higher (p<0.0001) in Graves' disease than in painless thyroiditis, subacute thyroiditis, or normal controls. The TBF of patients with Graves' disease was consistently >4%, and all other patients had TBF <4%, indicating that 4% is the cutoff for distinguishing destruction-induced thyrotoxicosis and Graves' disease [55]. Patients with Graves' disease show an approximately 15-fold higher TBF measured in mL/ min compared with normal and high peak systolic velocity flow on spectral Doppler in the medium-sized perithyroid and intra-thyroid arteries [56].…”

Section: Conventional B-mode Ultrasoundmentioning

confidence: 99%

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

et al. 2017

View full text Add to dashboard Cite

Accurate differentiation of focal thyroid nodules (FTL) and thyroid abnormalities is pivotal for proper diagnostic and therapeutic work-up. In these two part articles, the role of ultrasound techniques in the characterization of FTL and evaluation of diffuse thyroid diseases is described to expand on the recently published World Federation in Ultrasound and Medicine (WFUMB) thyroid elastography guidelines and review how this guideline fits into a complete thyroid ultrasound exam.

show abstract

Quantitative measurement of thyroid blood flow for differentiation of painless thyroiditis from Graves’ disease

Cited by 113 publications

References 24 publications

Menstrual disturbances in various thyroid diseases

Menstrual disturbances in various thyroid diseases

Association Between Plantar Fascia Vascularity and Morphology and Foot Dysfunction in Individuals With Chronic Plantar Fasciitis

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

Contact Info

Product

Resources

About