This study aims to analyze the factors of indoor environment on occupants' health and comfort by post-occupancy evaluation (POE) and to accumulate the fundamental data of occupants' behaviour in relation to indoor environment, in an effort to ascertain the optimal building energy management system (BEMS). For this purpose, indoor temperature, relative humidity, vertical temperature distribution, air velocity, predicted mean vote (PMV), radiant temperature, outdoor temperature, and humidity were measured for evaluating thermal environment for nearly 2 years. Indoor air contaminants, such as PM 10 , CO 2 , formaldehyde, and volatile organic compounds (VOCs) were measured in the building and at outdoor locations. Working plane illuminance, window luminance, and the equivalent continuous a-weighted sound pressure level (Leq) were also monitored. In addition, the occupants in the intelligent office building were surveyed regarding the indoor environmental quality via the intranet. Results showed that all indoor environmental factors satisfied the recommendation, except the indoor relative humidity and PMV. The physical factors of thermal environment had been stable since two months after it was built. However, it should be necessary to improve the sound privacy caused by low background noise, seasonal air-conditioning for appropriate humidity, air freshness, and Video Display Terminal (VDT) glare in order to reduce the level of occupants' annoyance.