Quantitative structure-activity relationship study of ATP-sensitive potassium channel openers: Derivatives of 3-alkylamino-4<i>H</i>-1,2,4-benzothiadiazine 1,1-dioxide

Sharma, B. K.; Singh, Prithvi; Sharma, S. K.

doi:10.1080/14756360701442381

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Qsrr-based Study Of Nucleosides and Pterins1

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Cited by 7 publications

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“…Additionally, pterins and nucleosides more likely act as a -type electron donors during the chromatographic process [43]. Mor31m and Mor04v descriptors belong to 3D MoRSE block from GETAWAY (GEometry, Topology, and Atom-Weights Assembly) class of descriptors [44]. Mor31m characterizes electron diffraction of a molecule's structure [45] and MATS1e represents electronegativity of the compound [46].…”

Section: Qsrr-based Study Of Nucleosides and Pterinsmentioning

confidence: 99%

Least absolute shrinkage and selection operator and dimensionality reduction techniques in quantitative structure retention relationship modeling of retention in hydrophilic interaction liquid chromatography

Daghir-Wojtkowiak

Wiczling

Bocian

et al. 2015

Journal of Chromatography A

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Section: Qsrr-based Study Of Nucleosides and Pterinsmentioning

confidence: 99%

Least absolute shrinkage and selection operator and dimensionality reduction techniques in quantitative structure retention relationship modeling of retention in hydrophilic interaction liquid chromatography

Daghir-Wojtkowiak

Wiczling

Bocian

et al. 2015

Journal of Chromatography A

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Synthesis, spectral characterization and biological studies of transition metal(II) complexes with triazole Schiff bases

Hanif

Chohan

2012

Applied Organom Chemis

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New metal based triazoles (1-12) have been synthesized by the interaction of novel Schiff base ligands (L 1 -L 3 ) with the Co(II), Ni(II), Cu(II) and Zn(II) metal ions. The Schiff base ligands and their all metal(II) complexes have been thoroughly characterized using various physical, analytical and spectroscopic techniques. In vitro bacterial and fungal inhibition studies were carried out to examine the antibacterial and antifungal profile of the Schiff bases in comparison to their metal(II) complexes against two Gram-positive, four Gram-negative and six fungal strains. The bioactivity data showed the metal(II) complexes to have more potent antibacterial and antifungal activity than their uncomplexed parent Schiff bases against one or more bacterial and fungal species. R Scheme 1. Preparation of the Schiff base ligands (L 1 -L 3 ). Scheme 2. Proposed structure of the metal(II) complexes (1-12).Synthesis, triazole Schiff bases, metal complexes, biological activity Average of ligands (L 1 -L 3 ) = 13.47 mm; average of complexes (1-12) = 17.24 mm.

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Ion Channels and Their Inhibitors

Gupta¹

2011

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Quantitative structure-activity relationship study of ATP-sensitive potassium channel openers: Derivatives of 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide

Cited by 7 publications

References 40 publications

Least absolute shrinkage and selection operator and dimensionality reduction techniques in quantitative structure retention relationship modeling of retention in hydrophilic interaction liquid chromatography

Least absolute shrinkage and selection operator and dimensionality reduction techniques in quantitative structure retention relationship modeling of retention in hydrophilic interaction liquid chromatography

Synthesis, spectral characterization and biological studies of transition metal(II) complexes with triazole Schiff bases

Ion Channels and Their Inhibitors

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