Quantum dot monolayer for surface plasmon resonance signal enhancement and DNA hybridization detection

Ghrera, Aditya Sharma; Pandey, Manoj Kumar; Malhotra, Bansi D.

doi:10.1016/j.bios.2016.02.013

Cited by 38 publications

(13 citation statements)

References 27 publications

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“…The detection of binding kinetics of DNA hybridization plays an important role in the diagnosis of diseases, [1][2][3][4][5] treatment of pathogen infections 3 and forensic tests. 4,5 To date, a variety of methods have been studied for the detection of DNA hybridization which mainly include optical [6][7][8] and electrochemical methods. [9][10][11] Among the optical methods, label-free surface plasmon resonance (SPR) is the standard tool for DNA binding detection.…”

Section: Introductionmentioning

confidence: 99%

An electricity-fluorescence double-checking biosensor based on graphene for detection of binding kinetics of DNA hybridization

et al. 2017

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Section: Introductionmentioning

confidence: 99%

An electricity-fluorescence double-checking biosensor based on graphene for detection of binding kinetics of DNA hybridization

et al. 2017

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“…Besides metal NPs, semiconductor QDs are also involved for the decoration of SPR metal films. It was demonstrated that semiconductor QDs will experience an electric separation process by transferring the conduction band electrons to Au NPs [51,52,53]. In this charging process of Au NPs, because the localized surface plasmon (LSPR) of Au NPs experiences electric coupling with surface plasmon of the gold film along the metal-dielectric interface, not only Au NPs will exhibit LSPR shifts, but also the surface plasmon of the Au film will be altered, inducing changes in SPR signals.…”

Section: Optical Sensingmentioning

confidence: 99%

Advances in Molecularly Imprinting Technology for Bioanalytical Applications

Feng

Pan

et al. 2019

Sensors

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In recent years, along with the rapid development of relevant biological fields, there has been a tremendous motivation to combine molecular imprinting technology (MIT) with biosensing. In this situation, bioprobes and biosensors based on molecularly imprinted polymers (MIPs) have emerged as a reliable candidate for a comprehensive range of applications, from biomolecule detection to drug tracking. Unlike their precursors such as classic immunosensors based on antibody binding and natural receptor elements, MIPs create complementary cavities with stronger binding affinity, while their intrinsic artificial polymers facilitate their use in harsh environments. The major objective of this work is to review recent MIP bioprobes and biosensors, especially those used for biomolecules and drugs. In this review, MIP bioprobes and biosensors are categorized by sensing method, including optical sensing, electrochemical sensing, gravimetric sensing and magnetic sensing, respectively. The working mechanism(s) of each sensing method are thoroughly discussed. Moreover, this work aims to present the cutting-edge structures and modifiers offering higher properties and performances, and clearly point out recent efforts dedicated to introduce multi-sensing and multi-functional MIP bioprobes and biosensors applicable to interdisciplinary fields.

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“…In particular, the high sensitivity in optical plasmonic sensors arises from locally enhanced density of photonic modes near where plasmons are excited [ 56 , 61 , 62 , 63 , 64 , 65 , 66 ]. When bringing target biomolecules of non-negligible molecular weight such as CRP molecules (molecular weight of 118–144 kDa [ 67 ]) into close proximity with a plasmonic metal surface, their strong interaction with the plasmonic local fields modifies the optical resonance condition via the effective refractive index change.…”

Section: Introductionmentioning

confidence: 99%

Plasmonic Optical Biosensors for Detecting C-Reactive Protein: A Review

Seok

2020

Micromachines

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C-reactive protein (CRP), a potent acute-phase reactant that increases rapidly in response to inflammation, tissue damage or infections, is also considered an indicator of the risk of cardiovascular diseases and neurological disorders. Recent advances in nanofabrication and nanophotonic technologies have prompted the optical plasmonic phenomena to be tailored for specific detection of human serum CRP into label-free devices. We review the CRP-specific detection platforms with high sensitivity, which feature the thin metal films for surface plasmon resonance, nano-enhancers of zero dimensional nanostructures, and metal nanoparticles for localized surface plasmon resonance. The protocols used for various types of assay reported in literature are also outlines with surface chemical pretreatment required for specific detection of CRPs on a plasmonic surface. Properties including sensitivity and detection range are described for each sensor device reviewed, while challenges faced by plasmonic CRP sensors are discussed in the conclusion, with future directions towards which research efforts need to be made.

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Quantum dot monolayer for surface plasmon resonance signal enhancement and DNA hybridization detection

Cited by 38 publications

References 27 publications

An electricity-fluorescence double-checking biosensor based on graphene for detection of binding kinetics of DNA hybridization

An electricity-fluorescence double-checking biosensor based on graphene for detection of binding kinetics of DNA hybridization

Advances in Molecularly Imprinting Technology for Bioanalytical Applications

Plasmonic Optical Biosensors for Detecting C-Reactive Protein: A Review

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