Quantum dots in cell imaging and their safety issues

Xu, Quan; Gao, Jiajia; Wang, Siyang; Wang, Yi; Liu, Dong; Wang, Juncheng

doi:10.1039/d1tb00729g

Cited by 74 publications

(48 citation statements)

References 113 publications

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“…Still, the cytotoxicity of CDs has raised much concern 404–406 since the toxicity of bare CDs is often dose and time dependent. 407 Surprisingly, there has been a report stating that CDs derived from the same precursors, but with different synthesis methods, demonstrated different cytotoxicities. 408 As such, researchers should devote more efforts to study and evaluate the bio-related properties of bare CDs.…”

Section: Discussionmentioning

confidence: 99%

Carbon dot composites for bioapplications: a review

Chen

Jia

et al. 2022

J. Mater. Chem. B

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Section: Discussionmentioning

confidence: 99%

Carbon dot composites for bioapplications: a review

Chen

Jia

et al. 2022

J. Mater. Chem. B

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“…The following chemical shift (δ) regions were discovered in the 1 H NMR spectrum (Fig. 5a): 1-3 ppm (dominated by sp 3 C-H protons), 3-6 ppm (associated with protons of hydroxyl, ether, and carbonyl groups), 6-8 ppm (for aromatic or sp 2 protons), and 8-10 ppm (related to aldehydic protons) [50]. The 1 H NMR spectrum in Fig.…”

Section: 1composition Structure and Morphology Analysismentioning

confidence: 91%

“…The 1 H NMR spectrum in Fig. 5a shows that the first two regions mentioned above are dominated over the last two regions, indicating that sp 3 -hybridized carbon atoms are dominated over sp 2 -hybridized carbon atoms. Carbon quantum dots are indeed mixed with sp 3 and sp 2 -hybridized carbon atoms.…”

Section: 1composition Structure and Morphology Analysismentioning

confidence: 97%

“…5b). There were four distinct regions found, namely 20-80 ppm (for sp 3 carbons as well as carbons attached with hydroxyl groups), 80-100 ppm (for carbons attached with ether linkages), 100-120 ppm (for C=C aromatic or sp 2 hybridized carbon atoms), and finally 175-190 ppm (for C=O carbons) [51][51].…”

Section: 1composition Structure and Morphology Analysismentioning

confidence: 99%

“…Carbonaceous and carbon-based nanomaterials have received a great deal of interest in recent years because to their enormous potential for practical applications in photocatalysis, optoelectronics, biomedicines, thin film displays, drug delivery, and other engineering and medical disciplines [1][2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Microwave-Assisted Green Synthesis of Carbon Quantum Dots Derived from Calotropis Gigantea as a Fluorescent Probe for Bioimaging

Sharma

Bera

2022

J Fluoresc

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In this study, an eco-friendly, cost-effective, and convenient method for preparing biocompatible fluorescent carbon quantum dots (CQDs) by one-pot microwave assisted synthesis from the leaf extract of the medicinal plant Calotropis gigantea, also known as crown flower, has been demonstrated. As-synthesized CQDs demonstrated fluorescence quantum yields up to 4.24 percent. The size distribution of the as-synthesized CQDs varied from 2.7 to 10.4 nm, with a significant proportion of sp 2 and sp 3 carbon groups verified by nuclear magnetic resonance analysis.The zeta potential of as-synthesized CQDs was measured to be -13.8 mV, indicating the existence of a negatively charged surface with incipient instability in aqueous suspension. Furthermore, as an alternative to organic or synthetic dyes, the development of simple, inexpensive, and non-destructive fluorescence-based staining agents are highly desired. In this regard, as-synthesized CQDs shown remarkable fluorescent staining capabilities in this work and may be utilised as a suitable probe for optical and bio-imaging of bacteria, fungi, and plant cells.

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Lead‐Free Halide Double Perovskites: Fundamentals, Challenges, and Photovoltaics Applications

Tailor

Listorti

Colella

et al. 2022

Adv Materials Technologies

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Metal halide perovskites (MHPs) have gained tremendous interest in photovoltaics applications reaching the power conversion efficiency (PCE) of 25.8%. Despite the rapid development of MHP‐based solar cells, the existence of toxic lead (Pb) and their operational instability are seen as key roadblocks for commercialization. A viable strategy for developing lead‐free optoelectronic devices nests in addressing the toxicity issues in these compounds by carefully and strategically replacing lead while maintaining comparable stability and PCE. In this regard, halide double perovskite with structural flexibility, as well as lower toxicity and higher stability have caught the attention of the scientific community, surging the research of lead‐free halide double perovskites with A2B(I)B(III)X6 composition. A critical analysis of such compounds is presented from a fundamental point of view considering their orbital characteristics, bonding interaction, and optical transitions and relate these properties with their solar cell performance. This review focuses on the efficiency limiting factors and critically discusses recent advancements and strategies which have been demonstrated to boost their photovoltaic performances. Finally, starting from existing double perovskite materials, prospective research directions are identified toward enhanced optoelectronic properties and device performances.

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Quantum dots in cell imaging and their safety issues

Abstract: When quantum dots are used as fluorescent probes or drug tracers for in vivo imaging, the quantum dots in the blood will come into direct contact with vascular endothelial cells....

Cited by 74 publications

References 113 publications

Carbon dot composites for bioapplications: a review

Carbon dot composites for bioapplications: a review

Microwave-Assisted Green Synthesis of Carbon Quantum Dots Derived from Calotropis Gigantea as a Fluorescent Probe for Bioimaging

Lead‐Free Halide Double Perovskites: Fundamentals, Challenges, and Photovoltaics Applications

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