We canonically quantize the dynamics of the brane universe embedded into the five-dimensional Schwarzschild-anti-deSitter bulk space-time. We show that in the brane-world settings the formulation of the quantum cosmology, including the problem of initial conditions, is conceptually more simple than in the 3+1-dimensional case. The Wheeler-deWitt equation is a finite-difference equation. It is exactly solvable in the case of a flat universe and we find the ground state of the system. The closed brane universe can be created as a result of decay of the bulk black hole.Introduction. Quantum effects almost certainly played crucial role in the early universe evolution and in the process of universe creation. Understanding and study of quantum cosmology is important not only from the conceptual point of view, but, hopefully, may provide us with constraints on possible topology of the universe and initial conditions for the inflationary stage [1,2,3]. Appropriate theoretical frameworks which would incorporate all quantum gravitational effects are yet to be constructed, however.String theory, eventually, may provide the consistent approach to the quantum cosmology realm, but the formulation of the string theory on a non-trivial and significantly Lorentzian space time is very complicated and unsolved task ( see for example [4] and references therein). That is why the approaches based on canonical quantization of the Einstein gravity [5] still prove to be more successful in addressing the problems of quantum cosmology. Here one has to adopt a modest approach and restrict consideration to quantum phenomena below the Plank energy scale. Quantizing the universe as a whole one has further resort to the "mini-superspace" modeling [1,2,3,6] in order to get to definite final results (for a recent interesting development see, however, Ref. [7] where effective action for the scale factor was derived integrating out other gravitational degrees of freedom using numerical simulations).Even then, within the "mini-superspace" approach, many conceptual and technical problems remain, such as the problem of ascribing physical meaning to the wave function of the universe [6]. Other important issues are the choice of the boundary conditions which one imposes at the big-bang point (e.g. "no-boundary" [6], "tunneling" [2], etc.) and the problem of unboundedness of the gravitational action (see e.g. [8]).In the present paper we pursue the viewpoint that the presence of extra dimensions can resolve or relax some of these problems. Indeed, in the brane world scenario [9,10], the problem of quantum cosmology (i.e. quantization of gravitational degrees of freedom) is replaced by a much better defined problem of quantum mechanics of the brane (matter degrees of freedom) which moves in the bulk space-time. This has several important consequences. First, one may hope that probabilistic inter-