In this paper, we investigate the following quasilinear elliptic and singular system (P):where Ω is a bounded domain with smooth boundary in R N , 1 < p, q < ∞ and f 1 , f 2 ∈ C 1 (Ω × R * + × R * + ) two positive functions. Under suitable conditions on f 1 and f 2 , we first give a general result on the existence of positive weak solutions pairs (u, v) ∈ W 1,p 0 (Ω)× W 1,q 0 (Ω) to (P). Next, we give some applications to Biology.