Quenching of Salicylaldehyde‐based Luminescence Probe via Dakin Reaction: Approach for Highly Selective Detection of Hydrogen Peroxide

Abstract

A novel assay for H 2 O 2 based on luminescence quenching is developed from the Dakin reaction between deprotonated salicylaldehyde (D-SA) and H 2 O 2 . Under alkaline condition, the phenolic hydroxyl group of SA is deprotonated, exhibiting good luminescence emission ability (λ ex = 433 nm, λ em = 508 nm). Luminescence of D-SA is quenched by H 2 O 2 in a concentration-dependent manner. Good linearity is obtained with a regression coefficient of 0.9989 in the range of 0.3~150 μM and a detection limit (LOD) is 30 nM. In addition, D-SA luminescence probe shows good biocompatibility and low cytotoxicity to HeLa cells through MTT assay. The feasibility for in vitro applications is demonstrated through confocal laser scanning microscopy.

Terbium Tetra‐Sulfosalicylate Complex as Quantitative Luminescent Sensing of Chromate Ions with High Selectivity and Sensitivity

“…Lanthanide nanomaterials and complexes play important roles in inorganic chemistry and materials science fields, because of their unique spectroscopic properties and 4f electronic orbital being shielded by the 5s 2 and 5p 6 shells . Lanthanide luminescence has attracted tremendous interest for use in lanthanide liquid crystal displays, electroluminescent materials, biological imaging, multiphoton‐excitation probes, and luminescence sensing, resulting in potential applications in electroluminescent devices, magnetic resonance imaging (MRI) agents, solar‐energy‐conversion devices, or luminescence‐response probes for biological testing .…”