Questionable sound exposure outside of the womb: frequency analysis of environmental noise in the neonatal intensive care unit

Lahav, Amir

doi:10.1111/apa.12816

Cited by 46 publications

(33 citation statements)

References 30 publications

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“…These findings can also be interpreted in the context of the infants' abilities to extract regularities during specific dynamic pattern exposures (here music) creating thus a kind of early perceptual habit as defined by Graybiel (2008). Furthermore, extensive research has shown that noise levels in NICUs are often higher than general recommendations (White et al, 2013;Lahav, 2015) This loud noise has a negative effect on the stability of the cardio-respiratory system, behavior and sleep of the preterm infants (Aly and Ahmed, 2016;Joshi and Tada, 2017) and is presumed to have long lasting effects in preterm infants language and behavioral development (Lahav and Skoe, 2014). Our results support the view that preterm infants can learn from their auditory environment and that preterm infants could have memory also for auditory dis-stimulation and thus warrant for ambient noise reduction in NICU.…”

Section: Discussionmentioning

confidence: 95%

Music processing in preterm and full-term newborns: A psychophysiological interaction (PPI) approach in neonatal fMRI

et al. 2019

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A B S T R A C TNeonatal Intensive Care Units (NICU) provide special equipment designed to give life support for the increasing number of prematurely born infants and assure their survival. More recently NICU's strive to include developmentally oriented care and modulate sensory input for preterm infants. Music, among other sensory stimuli, has been introduced into NICUs, but without knowledge on the basic music processing in the brain of preterm infants. In this study, we explored the cortico-subcortical music processing of different types of conditions (Original music, Tempo modification, Key transposition) in newborns shortly after birth to assess the effective connectivity of the primary auditory cortex with the entire newborn brain. Additionally, we investigated if early exposure during NICU stay modulates brain processing of music in preterm infants at term equivalent age. We approached these two questions using Psychophysiological Interaction (PPI) analyses. A group of preterm infants listened to music (Original music) starting from 33 weeks postconceptional age until term equivalent age and were compared to two additional groups without music intervention; preterm infants and full-term newborns. Auditory cortex functional connectivity with cerebral regions known to be implicated in tempo and familiarity processing were identified only for preterm infants with music training in the NICU. Increased connectivity between auditory cortices and thalamus and dorsal striatum may not only reflect their sensitivity to the known music and the processing of its tempo as familiar, but these results are also compatible with the hypothesis that the previously listened music induces a more arousing and pleasant state. Our results suggest that music exposure in NICU's environment can induce brain functional connectivity changes that are associated with music processing.

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Section: Discussionmentioning

confidence: 95%

Music processing in preterm and full-term newborns: A psychophysiological interaction (PPI) approach in neonatal fMRI

et al. 2019

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“…Because exposure to noise during early development is a highly probable occurrence, particularly for preterm infants exposed to life-support systems (Surenthiran et al, 2003;Lahav, 2014;Laubach et al, 2014;Park et al, 2014), a better understanding of the effects of noise-induced damage on ribbon synapses during early development is important for the formulation of noise safety guidelines. Thus, the present study examined the effects of noise-induced silent damage on ribbon synapses in neonatal mice during the early onset of hearing.…”

Section: Introductionmentioning

confidence: 99%

Noise-induced damage to ribbon synapses without permanent threshold shifts in neonatal mice

Shi¹,

Guo²,

Shen³

et al. 2015

Neuroscience

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Recently, ribbon synapses to the hair cells (HCs) in the cochlea have become a novel site of interest in the investigation of noise-induced cochlear lesions in adult rodents (Kujawa and Liberman, 2009; Lin et al., 2011; Liu et al., 2012; Shi et al., 2013). Permanent noise-induced damage to this type of synapse can result in subsequent degeneration of spiral ganglion neurons (SGNs) in the absence of permanent changes to hearing sensitivity. To verify whether noise exposure during an early developmental period produces a similar impact on ribbon synapses, the present study examined the damaging effects of noise exposure in neonatal Kunming mice. The animals received exposure to broadband noise at 105-decibel (dB) sound pressure level (SPL) for 2h on either postnatal day 10 (P10d) or postnatal day 14 (P14d), and then hearing function (based on the auditory brainstem response (ABR)) and cochlear morphology were evaluated during either postnatal weeks 3-4 (P4w) or postnatal weeks 7-8 (P8w). There were no significant differences in the hearing threshold between noise-exposed and control animals, which suggests that noise did not cause permanent loss of hearing sensitivity. However, noise exposure did produce a significant loss of ribbon synapses, particularly in P14d mice, which continued to increase from P4w to P8w. Additionally, a corresponding reduction in the amplitude of compound action potential (CAP) was observed in the noise-exposed groups at P4w and P8w, and the CAP latency was elongated, indicating a change in synaptic function.

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“…In addition, the hospital environment contains a significant amount of high-frequency electronic sounds (52,53) that are less likely to be heard in the womb because of the sound attenuation provided by maternal tissues and fluid within the intrauterine cavity (54)(55)(56). Efforts to improve the hospital environment for preterm neonates have primarily focused on reducing hospital noise and maintaining a quiet environment.…”

mentioning

confidence: 99%

Mother’s voice and heartbeat sounds elicit auditory plasticity in the human brain before full gestation

Webb¹,

Heller

Benson

et al. 2015

Proc. Natl. Acad. Sci. U.S.A.

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195

106

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Brain development is largely shaped by early sensory experience. However, it is currently unknown whether, how early, and to what extent the newborn's brain is shaped by exposure to maternal sounds when the brain is most sensitive to early life programming. The present study examined this question in 40 infants born extremely prematurely (between 25-and 32-wk gestation) in the first month of life. Newborns were randomized to receive auditory enrichment in the form of audio recordings of maternal sounds (including their mother's voice and heartbeat) or routine exposure to hospital environmental noise. The groups were otherwise medically and demographically comparable. Cranial ultrasonography measurements were obtained at 30 ± 3 d of life. Results show that newborns exposed to maternal sounds had a significantly larger auditory cortex (AC) bilaterally compared with control newborns receiving standard care. The magnitude of the right and left AC thickness was significantly correlated with gestational age but not with the duration of sound exposure. Measurements of head circumference and the widths of the frontal horn (FH) and the corpus callosum (CC) were not significantly different between the two groups. This study provides evidence for experience-dependent plasticity in the primary AC before the brain has reached full-term maturation. Our results demonstrate that despite the immaturity of the auditory pathways, the AC is more adaptive to maternal sounds than environmental noise. Further studies are needed to better understand the neural processes underlying this early brain plasticity and its functional implications for future hearing and language development. auditory | brain | mother's voice | heartbeat | preterm newborns

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Questionable sound exposure outside of the womb: frequency analysis of environmental noise in the neonatal intensive care unit

Cited by 46 publications

References 30 publications

Music processing in preterm and full-term newborns: A psychophysiological interaction (PPI) approach in neonatal fMRI

Music processing in preterm and full-term newborns: A psychophysiological interaction (PPI) approach in neonatal fMRI

Noise-induced damage to ribbon synapses without permanent threshold shifts in neonatal mice

Mother’s voice and heartbeat sounds elicit auditory plasticity in the human brain before full gestation

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