An increase in the volume of mining, large power plants, metallurgy, chemistry and machine building enterprises, as well as an increase in the number of motor vehiles in Kuzbass have a negative impact on the ecological state of the region, which, in turn, negatively affects the well-being and health of the population. According to the World Health Organization, 30–40% of life expectancy depends on the quality of the environment. The purpose of the study is to assess the environmental safety for the population of Kemerovo region. Using various research methods, statistical data were studied and summarized, regulatory documents were analyzed, and comparisons and calculations of environmental indicators were made. In particular, the risks of exposure to non-carcinogenic and carcinogenic substances were calculated. The hazard coefficient was used to determine to what extent the presence of each pollutant in the air has a negative impact, and which organ of the human body is exposed to the negative impact. The absence of a threat to public health was revealed. However, it is necessary to control emissions, since the risk can exceed the acceptable level. Possible sources of negative impacts are compared with the list of pollutants in the air. Measures to reduce the negative impact of pollutants on the environment on the example of Kemerovo were suggested.