Quick system design of vesicle-based active transport molecular communication by using a simple transport model

Abstract

a b s t r a c tThis paper will provide a guidepost to design an optimal molecular communication setup and protocol. A barrier to the design of vesicle-based molecular communication nanonetworks is the computational complexity of simulating them. In this paper, a computationally efficient transport model is presented, which could be employed to design active transport molecular communication systems, particularly to optimize the shape of the transmission zone. Furthermore, a vesicular encapsulation model is presented as an addition to the transport model, and it is shown that there exists an optimal vesicle size for each molecular communication channel. As an application, our transport model is used to estimate the channel capacity of a molecular communication nanonetwork in a computationally efficient manner compared to traditional Monte Carlo techniques. Moreover, it is shown that the derived optimal vesicle size maximizes channel capacity.

A mathematical channel optimization formula for active transport molecular communication

“…For our Monte Carlo simulations we use the same simulation techniques presented in [12] with the following parameters: simulation time steps of ΔT = 0.1 seconds, MT diffusion coefficient D = 2.0 · 10 −3 μm 2 /s, average speed of the MT v avg = 0.5 μm/s, and persistence length of the MT trajectory L p = 111 μm. We also assume the size of the information particles is 1μm, the average length of the MTs is 10μm, and each MT can load up to 5 information particles in one trip from the transmission zone to the receiver zone.…”

“…Related works in this field include a general formulation of molecular communication as a timing channel under Brownian motion [3], [4], an analysis of information transfer rates using molecular motors [5], [6], mathematical channel models for continuous diffusion [7], binary concentration-encoded molecular communication [8]. Concerning active transport molecular communication, in [9], [10] basic channel design is considered for designing molecular sorters and rectifiers.Our previous work includes a simple mathematical transport model for active transport propagation [11], and optimization of the transmission zone and vesicular encapsulation [12].In this work we extend our earlier work on transmission zone design, and consider the optimization of channel shape in active transport molecular communication. Design and optimization of these channels in wet labs are extremely time consuming and laborious.…”

“…Our previous work includes a simple mathematical transport model for active transport propagation [11], and optimization of the transmission zone and vesicular encapsulation [12].…”

“…Concerning active transport molecular communication, in [9], [10] basic channel design is considered for designing molecular sorters and rectifiers. Our previous work includes a simple mathematical transport model for active transport propagation [11], and optimization of the transmission zone and vesicular encapsulation [12].…”

Energy model for vesicle-based active transport molecular communication

“…Some of the prior work that have considered ATMC from a communication engineering perspective include: a complete simulation environment for ATMC in [16], different mathematical models for the ATMC in [17], and the channel design and optimization of ATMC in [18]- [20].…”