Quinoxaline-based Schiff base transition metal complexes: review

Dhanaraj, C. Justin; Johnson, Jijo; Joseph, J.; Joseyphus, R. Selwin

doi:10.1080/00958972.2013.782008

Cited by 92 publications

(28 citation statements)

References 62 publications

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“…Transition metal complexes with various oxidation states has a strong role in bioinorganic chemistry and may give a model basis for active sites of biological systems . Quinoline complexes are of much importance in today's world as they are used for various chemical, clinical as well as biological applications . Medicinally quinoline has been used in various areas, especially as an antimicrobial, antiprotozoal, antitubercular, antiviral, antiparasitic, antidiabetic, anti‐inflammatory, antihyperglycaemic, anticancer, antiplasmodial, antileishmanial and antiamoebic agent.…”

Section: Introductionmentioning

confidence: 99%

New dimeric Schiff base quinoline complexes: Synthesis, spectral characterization, electrochemistry and cytotoxicity

Ammar

Alaghaz

Alturiqi

2018

Applied Organom Chemis

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A novel Schiff base ligand (H-DPPMHQ) derived from 2-hydrazineylquinoline and 1,3-diphenyl-1H-pyrazole-5-carbaldehyde and its dimeric complexes with compositions [Cr(DPPMHQ)Cl] 2 ⋅2Cl and [M(DPPMHQ)Cl] 2 (where M = Cu(II), Co(II), Ni(II) and Zn(II)) have been synthesized and characterized using physicochemical methods like elemental analysis, magnetic susceptibility and molar conductivity measurements, multispectral techniques and electrochemical studies. The molar conductance data reveal that all metal chelates are non-electrolytes, except the Cr(III) complex which shows a Λ M value of 146.82 Ω −1 cm 2 mol −1 , indicating that it is a 1:2 electrolyte. Infrared spectral results show that the metal is organized through four nitrogen atoms (azomethine and deprotonated imine groups, pyrazole and quinoline rings) besides chlorine atoms. The NH proton is also displaced during complexation, as indicated by 1 H NMR spectral data. Based on the electron spin resonance and ligand field parameter data, the bonding parameters of these complexes have been calculated. Using Coats-Redfern and Horowitz-Metzger equations, thermodynamic parameters were determined. The spectral data indicate that the dimeric complexes have octahedral geometry around the central metal ions. The cytotoxic activities of all compounds were evaluated towards human breast cancer (MCF-7) and lung cancer (A549) cell lines.

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Section: Introductionmentioning

confidence: 99%

New dimeric Schiff base quinoline complexes: Synthesis, spectral characterization, electrochemistry and cytotoxicity

Ammar

Alaghaz

Alturiqi

2018

Applied Organom Chemis

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“…Schiff bases and their transition metal complexes are studied because of their wide range of possible applications [1][2][3]. Schiff base ligands with additional donors near the azomethine nitrogen are able to form stable chelates [3]. Conformational flexibility and large number of potential donors of 2,6-diacetylpyridine dihydrazones allow different modes of coordination to metal ions.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and antimicrobial activity of pentagonal-bipyramidal isothiocyanato Co(II) and Ni(II) complexes with 2,6-diacetylpyridine bis(trimethylammoniumacetohydrazone)

Brađan

Čobeljić

Pevec

et al. 2016

Journal of Coordination Chemistry

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Pentagonal-bipyramidal isothiocyanato Co(II) and Ni(II) complexes with condensation product of 2,6-diacetylpyridine and trimethylammoniumacetohydrazide (Girard's T reagent) were synthesized and characterized by elemental analyses, IR and UV-Vis spectra, molar conductivity and magnetic susceptibility. Crystal structures of the Co(II) and Ni(II) complexes were also determined. Antimicrobial activities of the ligand and metal complexes were examined.

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“…Compared with the complexes, three absorptions were observed at 234, 309 and 361 nm, respectively (ε = 19,986, 8,194, 4,088 mol −1 L cm −1 ) in the spectrum of HL 1 . The absorption at 247 nm (ε = 19,932 mol −1 L cm −1 ) in the complex could be assigned to π‐π* transition of phenyl rings . A new absorption peak at 433 nm (ε = 4,492 mol −1 L cm −1 ) was observed in 1 while at around 389 nm (ε = 5,237 mol −1 L cm −1 ) in 2 , which could be attributed to ligand‐to‐metal charge transfer (LMCT) transitions .…”

Section: Resultsmentioning

confidence: 94%

X‐ray structures, spectroscopic, electrochemical, thermal, antibacterial, and DFT studies of two nickel(II) and cobalt(III) complexes constructed from a new quinazoline‐type ligand

Chai

Zhang

et al. 2018

Applied Organom Chemis

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Two two‐dimensional supramolecular Nickel(II) and Cobalt(III) complexes, [Ni(L2)2]·2CH3OH (1) and [2Co(L2)2] (2) (HL2 = 1‐(2‐{[(E)‐3‐bromo‐5‐chloro‐2‐hydroxybenzylidene]amino}phenyl)ethanone oxime), were synthesized via complexation of salts acetate with HL1 (2‐(3‐bromo‐5‐chloro‐2‐hydroxyphenyl)‐4‐methyl‐1,2‐dihydroquinazoline 3‐oxide, H is the deprotonatable hydrogen). During the reaction, the C–N bond in HL1 is converted into the C=N–OH group in HL2. The spectroscopic data of both complexes were compared with the ligand HL1. HL1 and both complexes were determined by single‐crystal X‐ray crystallography. The differently geometric features of the obtained complexes 1 and 2 are observed. In the crystal structure, 1 and 2 form an infinite 1‐D chain‐like and 2‐D supramolecular frameworks. EPR spectroscopy of 2 was investigated. Moreover, electrochemical properties and antimicrobial activities of both complexes were also studied. In addition, the calculated HOMO and LUMO energies show the character of HL1, complexes 1 and 2. The electronic transitions and spectral features of HL1 and both complexes were discussed by TD‐DFT calculations.

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Quinoxaline-based Schiff base transition metal complexes: review

Cited by 92 publications

References 62 publications

New dimeric Schiff base quinoline complexes: Synthesis, spectral characterization, electrochemistry and cytotoxicity

New dimeric Schiff base quinoline complexes: Synthesis, spectral characterization, electrochemistry and cytotoxicity

Synthesis, characterization and antimicrobial activity of pentagonal-bipyramidal isothiocyanato Co(II) and Ni(II) complexes with 2,6-diacetylpyridine bis(trimethylammoniumacetohydrazone)

X‐ray structures, spectroscopic, electrochemical, thermal, antibacterial, and DFT studies of two nickel(II) and cobalt(III) complexes constructed from a new quinazoline‐type ligand

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