2013
DOI: 10.1097/ico.0b013e31825aba0e
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Quo Vadis Older Keratoconus Patients? Do They Die at Younger Ages?

Abstract: An absence or loss of older KC patients has been found in some specialist contact lens fitting practices. Notwithstanding the possible influence of numerous other issues, the absence or loss of KC patients may be because of reduced life expectancy, a topic that seems to warrant further examination. There may be implications for improving the understanding of the pathogenesis of KC if reduced life expectancy can be confirmed and the associated reasons elucidated.

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Cited by 16 publications
(10 citation statements)
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“…[9][10][11] What happens to affected patients later on in their life remains unknown. 12 The pathogenesis of keratoconus is complicated and includes environmental factors, atopy, and hereditary susceptibility. 13,14 Eye rubbing, contact lens wear, and ultraviolet radiation appear to be important factors.…”
mentioning
confidence: 99%
“…[9][10][11] What happens to affected patients later on in their life remains unknown. 12 The pathogenesis of keratoconus is complicated and includes environmental factors, atopy, and hereditary susceptibility. 13,14 Eye rubbing, contact lens wear, and ultraviolet radiation appear to be important factors.…”
mentioning
confidence: 99%
“…In the absence of symptoms, a delayed onset and diagnosis may represent a failure to examine for or detect changes due to early keratoconus, perhaps especially when methods based on recent technological advances were not or are not employed. Prevalence of keratoconus in older groups may be reduced by increased mortality rates . Comparisons with the upper limit of estimates of the prevalence of keratoconus made prior to 1966 (230 per 100,000) with the prevalence more recently found among candidates for refractive surgery suggest an increased prevalence.…”
Section: Increasing Prevalence or Better Detection?mentioning
confidence: 90%
“…The thinning and protrusion of the cornea can lead to visual loss and eventual need for corneal transplantation. Systemic diseases such as obstructive sleep apnea and mitral valve prolapse are associated with keratoconus [16]. Refractive surgery is contraindicated in patients with keratoconus because it can lead to post-surgical corneal thinning and blindness.…”
Section: Discussionmentioning
confidence: 99%