Racial and ethnic disparities in mortality from gastric and esophageal adenocarcinoma

Abstract

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Regional and racial disparity in proximal gastric cancer survival outcomes 1996–2016: Results from SEER and China National Cancer Center database

“…9 In fact, important differences have also been observed in gastric cancer presentation, anatomic location (proximal-cardia, fundus; distal-body, antrum, pylorus) and patients receipt of multimodality therapy and surgery. [2][3][4][5][6][7][8] Anatomic differences in location of gastric cancer between Western and Asian nations may contribute to such differences with proximal gastric cancer (PGC) being more prevalent in Western countries compared to distal gastric cancer (DGC) being more prevalent in Asian countries. [10][11][12] Given the growing incidence and aggressive biological behavior of PGC as reported, 12 it is important to understand which subpopulations are at worst prognosis of dying from each so that interventions can be treated appropriately.…”

“… 1 Notably, there are differences in incidence, prevalence and mortality of gastric cancer in different regions or races. 2 , 3 , 4 , 5 , 6 , 7 , 8 For example, notwithstanding the higher prevalence of gastric cancer in Asia, significantly better outcomes have been reported in Asia compared to Western counties. 9 In fact, important differences have also been observed in gastric cancer presentation, anatomic location (proximal‐cardia, fundus; distal‐body, antrum, pylorus) and patients receipt of multi‐modality therapy and surgery.…”

“… 9 In fact, important differences have also been observed in gastric cancer presentation, anatomic location (proximal‐cardia, fundus; distal‐body, antrum, pylorus) and patients receipt of multi‐modality therapy and surgery. 2 , 3 , 4 , 5 , 6 , 7 , 8 …”

Impact of Insurance Status on Late-Stage Disease Presentation and Disease-Specific Survival among US Patients With Gastric Cancer

“…8,9 However, some US racial and ethnic minority patients with GC have been shown to have poorer survival outcomes than Asian or Pacific Islander patients, despite having lower GC incidence rates. 10,11 Over the past decades, rates of the uninsured US populations have ranged from 10%-20%, with a higher proportion of racial and ethnic minority populations being uninsured, notably Hispanic and Black populations. 13,14 Insurance status serves as one reflection of a person's socioeconomic status and has an important function in offsetting financial difficulties that might affect overall cancer diagnosis and/or survival, including access to rehabilitation and follow-up visits.…”

Gastrointestinal Cancers: Racial and Ethnicity Differences

“…In one of the studies using Surveillance, Epidemiology, and End Results database higher mortality rates were reported in minority groups (blacks, Hispanics, and Asians/Paci c Islanders) compared to non-Hispanic whites among patients diagnosed with non-cardia gastric cancer, whereas for cardia gastric cancer mortality rates were marginally higher in middle aged non-Hispanic patients with advanced disease [11]. However, Japanese and Asian patients diagnosed with gastric cancer have been reported to have better overall survival compared to White patients [12].…”