Racial differences in fibroid prevalence and ultrasound findings in asymptomatic young women (18–30 years old): a pilot study

Abstract

Objectives 1) To determine the prevalence of fibroids in asymptomatic young black and white women (ages 18–30yo); 2) To determine other differences in uterine and adnexal anatomy; 3) To obtain preliminary data for sample size calculations. Design A pilot cross-sectional study. Setting An academic medical center Patients 101 non-parous black and white women, ages 18–30 years old, with no known diagnosis of fibroids or clinically suggestive symptoms. Interventions A transvaginal ultrasound was performed in the follicular phase in all subjects. Main Outcome Measure(s) 1) Presence of fibroids; 2) endometrial thickness; 3) ovarian findings. Results Of the 101 participants (mean age 24.5 ± 3.5), 43% self-identified as black and 57% as white. The prevalence of ultrasound-diagnosed fibroids was 15% overall (26% in black women and 7% in white women). The mean fibroid size was 2.3 ± 2.1 cm. There was a significant difference in endometrial thickness between races, even after adjusting for contraception use and fibroid presence. Conclusions Racial differences in fibroid prevalence exist even before women become symptomatic. Findings of thicker endometrium in black women could have clinical implications and warrants further investigation.

Intravenous Carbetocin to decrease blood loss during open myomectomy: a randomized placebo-controlled study

“…1 Approximately 20-40% of women with fibroids experience significant symptoms and consult gynaecologic care. 1 The most common clinical symptoms include abnormal uterine bleeding, dysmenorrhea, pelvic pain, infertility, and recurrent pregnancy loss.…”

Evaluation of serum cystatin C levels in fibroid patients in Elele

“…Fibroids can range in number and size from a single growth to multiple growths [1,2].The prevalence of fibroid varies between 5-65% depending on age, ethnicity ,geographical region and quality of imaging techniques [3][4][5].Some fibroids may interfere with pregnancy although this appears to be uncommon [6]). Both genetic factors such as mutations and environmental factors such as obesity have been implicated in the development of fibroids [6].…”

Evaluation of Serum Cystatin C Levels in Fibroid Patients in Elele

“…Fibroids can range in number and size from a single growth to multiple growths [1,2]. The prevalence of fibroid varies between 5-65% depending on age, ethnicity, geographical region and quality of imaging techniques [3][4][5]. Some fibroids may interfere with pregnancy although this appears to be uncommon [6].…”