We describe a case of a radial artery "mycotic" pseudoaneurysm with distal septic emboli to the hand caused by methicillin-resistant Staphylococcus aureus that developed 2 days after removal of a percutaneously placed arterial catheter. The diagnosis was confirmed at surgical exploration after a rapid increase in swelling and pain at the site. This is a rare complication that has been reported once in the last decade, and only a total of 22 cases were reported in the English literature.