The problem of producing a natural language description of an image for describing the visual content has gained more attention in natural language processing (NLP) and computer vision (CV). It can be driven by applications like image retrieval or indexing, virtual assistants, image understanding, and support of visually impaired people (VIP). Though the VIP uses other senses, touch and hearing, for recognizing objects and events, the quality of life of those persons is lower than the standard level. Automatic Image captioning generates captions that will be read loudly to the VIP, thereby realizing matters happening around them. This article introduces a Red Deer Optimization with Artificial Intelligence Enabled Image Captioning System (RDOAI-ICS) for Visually Impaired People. The presented RDOAI-ICS technique aids in generating image captions for VIPs. The presented RDOAI-ICS technique utilizes a neural architectural search network (NASNet) model to produce image representations. Besides, the RDOAI-ICS technique uses the radial basis function neural network (RBFNN) method to generate a textual description. To enhance the performance of the RDOAI-ICS method, the parameter optimization process takes place using the RDO algorithm for NasNet and the butterfly optimization algorithm (BOA) for the RBFNN model, showing the novelty of the work. The experimental evaluation of the RDOAI-ICS method can be tested using a benchmark dataset. The outcomes show the enhancements of the RDOAI-ICS method over other recent Image captioning approaches.