Radial Optic Neurotomy for Central Retinal Vein Occlusion

Opremcak, E. Mitchel; Rehmar, Alan J.; Ridenour, Chet D.; Kurz, Daryl E.

doi:10.1097/00006982-200603000-00008

Cited by 71 publications

(19 citation statements)

References 12 publications

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“…Several studies have reported variable visual improvement after RON ranging from none to 5 lines of vision [6, 7, 18,20,21,22,23, 26, 27]. Possible explanations for such differences may relate to case selection (differing number of patients and inclusion criteria) and study design (retrospective, different follow-up).…”

Section: Discussionmentioning

confidence: 99%

Radial Optic Neurotomy for Central Retinal Vein Occlusion: Long-Term Retinal Perfusion Outcome

Callizo¹,

Kroll²,

Mennel³

et al. 2009

Ophthalmologica

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Background/Aims:To analyze the long-term changes in retinal perfusion and functional improvement induced by radial optic neurotomy (RON) in central retinal vein occlusion (CRVO). Methods: Sixty-three eyes of 63 consecutive patients with CRVO were included. Twenty-eight (44.5%) patients underwent RON and 35 (55.5%) were followed as a control group. Time of arteriovenous transit and visual acuity were determined at baseline and after 1-year follow-up. Results:After 1 year, retinal perfusion status improved in 63.1% of operated eyes and 14.3% of controls (p = 0.048). The improvement in arteriovenous retinal transit was statistically significant (p = 0.023) only in the RON group. The visual improvement in the RON group was significantly better (p = 0.043) than in the control group. Moreover, the development of chorioretinal anastomosis was significantly higher (p = 0.036) after RON than in controls and correlated with better functional results. In operated eyes there was a lower incidence of CRVO-related complications. Conclusion:RON improved retinal perfusion and achieved a better functional outcome. The measurement of perfusion changes as presented here may be useful for monitoring CRVO and assessing other treatment modalities.

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Section: Discussionmentioning

confidence: 99%

Radial Optic Neurotomy for Central Retinal Vein Occlusion: Long-Term Retinal Perfusion Outcome

Callizo¹,

Kroll²,

Mennel³

et al. 2009

Ophthalmologica

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“…In a large-scale study which evaluated the outcomes of RON in 117 patients with severe CRVO, anatomic resolution was reported in 95% of patients, and visual improvement in 71% within 3 months postoperatively [117]. …”

Section: Surgical Approaches To Treating Rvomentioning

confidence: 99%

Management of Retinal Vein Occlusion – Consensus Document

et al. 2011

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Retinal vein occlusion (RVO) can have severe consequences for the people affected by the disease, including visual loss with costly social repercussions. Currently, there is no European consensus with regard to the management of RVO. Following a careful review of the medical literature as well as the data from several clinical trials, a collaborative group of retina specialists put forth practical recommendations based on the best available scientific evidence for the clinical approach to RVO. Taking into consideration the recent advances in diagnostic tools and management options, the present document aims to provide the European ophthalmologists with guidelines for clinical practice to the benefit of their patients.

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“…Some surgeons have also reported successful results with radial optic neurotomy (RON), but complications of the procedure have been reported. Opremcak et al[21,22,23] reported anatomic resolution of CRVO in 92–95% of 180 patients following RON with associated improvement in VA. Binder et al [24] found clinically relevant improvements on a long-term follow-up with RON; patients with nonischemic CRVO may respond more favorably than patients with ischemic CRVO. But when comparing both procedures, Yamamoto et al [25] concluded that although there was no significant difference in surgical outcomes between the two procedures, the therapies with tPA cannulation or RON alone were inadequate, because an additional treatment was necessary.…”

Section: Treatmentmentioning

confidence: 99%

“…Macular grid photocoagulation is an effective treatment to improve vision, but only for BRVO macular edema [2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30]. In CRVO, even if the treatment clearly reduces angiographic evidence of macular edema, macular grid photocoagulation results in no VA improvement [33].…”

Section: Treatmentmentioning

confidence: 99%

Retinal Vein Occlusion: Current Treatment

Lattanzio¹,

Gimeno

Parodi³

et al. 2010

Ophthalmologica

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Retinal vein occlusion (RVO) is a pathology noted for more than 150 years. Although a lot has been written on the matter, it is still a frequent condition with multifactorial etiopathogenesis with many unclear aspects. The RVO pathogenesis has varied systemic and local implications that make it difficult to elaborate treatment guidelines. The management of the patient with RVO is very complex and a multidisciplinary approach is required in order to identify and correct the associated risk factors. Laser therapy remains the gold standard in RVO, but only modest functional improvement has been shown in branch retinal occlusion forms. Multicenter studies of intravitreal drugs present them as an option to combine with laser. Anti-vascular endothelial growth factor, corticosteroids and sustained-release implants are the future weapons to stop disease progression and get a better visual outcome. Consequently, it is useful to clarify some aspects of the pathology that allow a better patient management.

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Radial Optic Neurotomy for Central Retinal Vein Occlusion

Abstract: Surgical decompression of CRVO via RON is a technically feasible and safe procedure that was associated with anatomical resolution of CRVO in 95% patients and improved visual function in 71%.

Cited by 71 publications

References 12 publications

Radial Optic Neurotomy for Central Retinal Vein Occlusion: Long-Term Retinal Perfusion Outcome

Radial Optic Neurotomy for Central Retinal Vein Occlusion: Long-Term Retinal Perfusion Outcome

Management of Retinal Vein Occlusion – Consensus Document

Retinal Vein Occlusion: Current Treatment

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