“…Once, materials such as medical absorbent cotton [1] and pledget [2] were widely used as wound dressings owing to them isolated the wound from outside environment. With the development of technology, it is found that wound healing is a series of events that is quite complex and incompletely understood [3]. During wound healing, wound barrier formation is a critical process.…”
“…Once, materials such as medical absorbent cotton [1] and pledget [2] were widely used as wound dressings owing to them isolated the wound from outside environment. With the development of technology, it is found that wound healing is a series of events that is quite complex and incompletely understood [3]. During wound healing, wound barrier formation is a critical process.…”
“…The broad band with less absorbance of CH bending around 2950 -2900 cm -1 was observed in Figure 1(c) compared to Figure 1(b) because of the formation of crosslink network of PVP (Singh & Pal 2011). The covalent bond of PVP crosslinked attributed by the weak vibration of -CH 2 -at 1420 cm -1 of hydrogel L. The aliphatic C-H stretch at 2880 cm -1 band indicated intense peak in PEG yet weakened in (e).…”
Section: Syneresismentioning
confidence: 90%
“…The broad absorption band around 1010 -1080 cm -1 of Figure1(a) attributes to the glycosidic linkages of LMC (Abad et al 2003). The strong band at 1653, 1421, 1287 and weak band at 2917 cm -1 of PVP Figure 1(b) were assigned to C=O stretching, C-N stretching, O-H bending and C-H stretching vibrations, respectively (Can 2005;Singh & Pal 2011;Yang et al 2010).…”
PEG at compositions of 10, 15 and 20 g were added into the initial formulation of hydrogel L, which was composed of 6 g low molecular weight chitosan (LMC)
“…However, the large scale skin defects could not heal spontaneously, which still is the major problem in the surgical field [1]. Since the early 1980s, numerous skin substitutes including autografts, allografts, and xenografts have been developed to promote wound healing [2].…”
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