Radiation Dose Reduction without Degradation of Low-Contrast Detectability at Abdominal Multisection CT with a Low–Tube Voltage Technique: Phantom Study

Funama, Yoshinori; Awai, Kazuo; Nakayama, Yoshiharu; Kakei, Kiyotaka; Nagasue, Nozomu; Shimamura, Masayoshi; Sato, Natsuko; Sultana, Shamima; Morishita, Shoji; Yamashita, Yasuyuki

doi:10.1148/radiol.2373041643

Cited by 211 publications

(123 citation statements)

References 23 publications

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“…ROIs were also drawn in the background of the lungs to assess the contrast‐to‐noise ratio (CNR) using the method described by Funama et al (6) Furthermore, ROIs were drawn in the background of the lungs and in the eight simulated GGOs in the multipurpose chest phantom to assess nodule noise and CNR.…”

Section: Methodsmentioning

confidence: 99%

Radiation dose reduction for CT lung cancer screening using ASIR and MBIR: a phantom study

Mathieu

Fox

et al. 2014

J Applied Clin Med Phys

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The purpose of this study was to reduce the radiation dosage associated with computed tomography (CT) lung cancer screening while maintaining overall diagnostic image quality and definition of ground‐glass opacities (GGOs). A lung screening phantom and a multipurpose chest phantom were used to quantitatively assess the performance of two iterative image reconstruction algorithms (adaptive statistical iterative reconstruction (ASIR) and model‐based iterative reconstruction (MBIR)) used in conjunction with reduced tube currents relative to a standard clinical lung cancer screening protocol (51 effective mAs (3.9 mGy) and filtered back‐projection (FBP) reconstruction). To further assess the algorithms' performances, qualitative image analysis was conducted (in the form of a reader study) using the multipurpose chest phantom, which was implanted with GGOs of two densities. Our quantitative image analysis indicated that tube current, and thus radiation dose, could be reduced by 40% or 80% from ASIR or MBIR, respectively, compared with conventional FBP, while maintaining similar image noise magnitude and contrast‐to‐noise ratio. The qualitative portion of our study, which assessed reader preference, yielded similar results, indicating that dose could be reduced by 60% (to 20 effective mAs (1.6 mGy)) with either ASIR or MBIR, while maintaining GGO definition. Additionally, the readers' preferences (as indicated by their ratings) regarding overall image quality were equal or better (for a given dose) when using ASIR or MBIR, compared with FBP. In conclusion, combining ASIR or MBIR with reduced tube current may allow for lower doses while maintaining overall diagnostic image quality, as well as GGO definition, during CT lung cancer screening.PACS numbers: 87.57.Q‐, 87.57.nf

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Section: Methodsmentioning

confidence: 99%

Radiation dose reduction for CT lung cancer screening using ASIR and MBIR: a phantom study

Mathieu

Fox

et al. 2014

J Applied Clin Med Phys

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“…For children and smaller adults, lower tube voltages may reduce dose and enable CNR equivalent to that obtained at higher tube voltages. [9][10][11][12] In this study, the system had 3 different tube voltage stations: 80, 120, and 140 kVp. Corresponding effective tube mAs values (540, 240, and 180 mAs/section), as shown in Table 3, were available to achieve the same x-ray flux; however, the measured CTDI vol with 80 kVp was only 14.5 mGy, 57.1% of the CTDI vol with 120 kVp, and 56.9% of the CTDI vol with 140 kVp.…”

Section: Discussionmentioning

confidence: 99%

Experimental Study and Optimization of Scan Parameters That Influence Radiation Dose in Temporal Bone High-Resolution Multidetector Row CT

Niu¹,

Olszewski²,

Zhang³

et al. 2011

AJNR Am J Neuroradiol

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“…Many advances have been made in decreasing radiation dose through aggressive decreases in tube current (9,10) and automatic tube current modulation (11)(12)(13)(14)(15). A decrease in tube voltage will also lead to a decrease in radiation dose at the expense of a potential increase in image noise (16). While radiation dose decreases linearly with a decrease in tube current, radiation dose decreases by a power of 2.6 with tube voltage reduction (17,18), which makes this a powerful technique with which to decrease radiation exposure.…”

Section: Patient Population and Bowel Preparationmentioning

confidence: 99%

Reducing Radiation Dose at CT Colonography: Decreasing Tube Voltage to 100 kVp

Chang¹,

Caovan²,

Grand³

et al. 2013

Radiology

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Purpose:To assess the effect of a decrease in tube voltage from 120 kVp to 100 kVp on dose, contrast-to-noise ratio (CNR), and three-dimensional (3D) image quality in patients undergoing computed tomographic (CT) colonography as well as to determine how these changes are affected by patient size. Materials and Methods:This HIPAA-compliant and institutional review board-approved retrospective study included 63 consecutive patients who underwent CT colonography and who waived informed consent. Scanning was performed with patients in the supine (120 kVp) and prone (100 kVp) positions, with other parameters unchanged. Volume CT dose index (CTDI vol ), dose-length product (DLP), image noise, attenuation of selected materials, and CNR were compared with the Wilcoxon matched-pairs signed rank test. Two readers blinded to tube voltage independently assessed 3D endoluminal image quality. The k coefficients were calculated for interobserver agreement. Average image quality ratings were compared with the Wilcoxon signed rank test. All recorded data were stratified by patient anteroposterior diameter to determine effects of patient size. Results:Decreasing tube voltage from 120 to 100 kVp resulted in a 20% decrease in CTDI vol (P , .001) and a 16% decrease in DLP (P , .001). Image noise increased by 32% (P , .001). Mean attenuation of tagged fluid increased from 395 to 487 HU (P , .001). There was no change in mean CNR of tagged fluid (17.1 at 120 kVp, 16.8 at 100 kVp; P = .37), regardless of patient size. The 3D image quality decreased slightly from a median score of 5 out of 5 to 4 out of 5 (P , .001). There was substantial interobserver agreement. Conclusion:A decrease in tube voltage from 120 to 100 kVp results in a significant decrease in radiation dose but only a minimal decrease in 3D image quality at all patient sizes.q RSNA, 2012

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Radiation Dose Reduction without Degradation of Low-Contrast Detectability at Abdominal Multisection CT with a Low–Tube Voltage Technique: Phantom Study

Abstract: A reduction from 120 kV to 90 kV led to as much as a 35% reduction in the radiation dose, without sacrifice of low-contrast detectability, at CT.

Cited by 211 publications

References 23 publications

Radiation dose reduction for CT lung cancer screening using ASIR and MBIR: a phantom study

Radiation dose reduction for CT lung cancer screening using ASIR and MBIR: a phantom study

Experimental Study and Optimization of Scan Parameters That Influence Radiation Dose in Temporal Bone High-Resolution Multidetector Row CT

Reducing Radiation Dose at CT Colonography: Decreasing Tube Voltage to 100 kVp

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