Radiation Protection of Vital Organs, Using a Selective Arterial Catheter

Three-hundred Balb/C mice were used to assess the effect of vasopressin on the response of the gastrointestinal tract to irradiation. Median lethal doses were determined for control and vasopressin treated animals in which the whole abdomen was irradiated. There was a significant difference in LD50/6 (882 +/- 27 for controls vs. 1051 +/- 23 for vasopressin-treated animals). In addition studies demonstrated a significant difference in the survival rate of jejunal crypts at 800 and 1,000 rads.

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A study of the radioprotective effect of vasopressin induced ischaemia on the small intestine of the dog and its relation to circulatory parameters

Borgström¹,

Aronsen²,

Dougan³

et al. 1982

BJR

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Radiation Protection of Vital Organs, Using a Selective Arterial Catheter

Cited by 6 publications

References 5 publications

Radiation protection of the normal kidney by selective arterial infusions

Radiation protection of the normal kidney by selective arterial infusions

The Radioprotective Effects of Vasopressin on the Gastrointestinal Tract of Mice

A study of the radioprotective effect of vasopressin induced ischaemia on the small intestine of the dog and its relation to circulatory parameters

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