Radiation synthesis and drug delivery properties of interpenetrating networks (IPNs) based on poly(vinyl alcohol)/ methylcellulose blend hydrogels

El‐Naggar, Abdel Wahab M.; Senna, Magdy M.; Mostafa, Tahia A.; Helal, Reham H.

doi:10.1016/j.ijbiomac.2017.04.084

Cited by 42 publications

(10 citation statements)

References 29 publications

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“…(20), with %R sum = 26.2 wt% and record release efficiency percentage of 66.7%. The CMC/Pb-CH hydrogel has shown minimum release in acidic and basic medium due to the ionic interaction with the ions of the release medium (El-Naggar et al, 2017). Whereas the CMC/P-b-PH hydrogel has shown its maximum release in basic medium and at 15 o C Fig.…”

Section: Studies On Degree Of Swelling (S W )mentioning

confidence: 96%

“…(5), one is endotherm of +45.8 J.g -1 , give indications that the hydrogel components (CMC and PVA) and the sodium ions present in the hydrogel would left the hydrogel has some crystalline portions in its morphology therefore it need energy of 45.8 joule per gram for decomposition of those crystalline portions. Whereas the -5.8 J.g -1 means the hydrogel has amorphous portions and on decomposition will liberate energy 5.8 Joule per gram of the hydrogel (El-Naggar et al, 2017).…”

Section: Thermal Studiesmentioning

confidence: 99%

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Studies on Preparation and Characterization of Blend Polymers for Hydrogels Synthesis and Use for Protein Release

Jabrail¹,

Al-Ojar²

2019

RJS

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Carboxy methyl cellulose, pectin, chitosan or acrylic acid-poly (vinyl alcohol) blend hydrogels were prepared using Glutaraldehyde (GLU) as chemical or sodium hexameta phosphate (SHMP) as physical cross-linking agent. The prepared hydrogels have carried the advantage properties of both blend materials and can be used for loading and releasing of BSA protein. The degree of swelling of the prepared hydrogels was measured due to their different functional groups in different pHs of (pH4, pH7 and pH9) in addition to the electrolyte solution of 0.1 N NaCl. The blend hydrogels are characterized for their chemical structure using FT-IR. The XRD analysis was investigated for determination of the hydrogels crystallographic structure. The differential thermal analysis DTA and scanning electron microscope SEM were depended to study the thermal stability and surface morphology of the hydrogel respectively. The hydrogels were loaded with BSA protein model, and time of loading at (1.5, 3.0, 4.5 and 6.0) hrs were measured, beside the pH of the loading solution of ph4, pH6 and pH8 were considered and the BSA concentrations of (0.5, 1.0, 1.5 and 2.0) g/L have been investigated for maximum loading percentages %L max of BSA on the hydrogels. Finally the loaded BSA was released under different release conditions in 0.9% w/vNaCl solution and pH4, pH6 and pH8 were depended and the BSA was tested to release at 15, 25 and 40 o C releasing medium temperatures.

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Section: Studies On Degree Of Swelling (S W )mentioning

confidence: 96%

Section: Thermal Studiesmentioning

confidence: 99%

Studies on Preparation and Characterization of Blend Polymers for Hydrogels Synthesis and Use for Protein Release

Jabrail¹,

Al-Ojar²

2019

RJS

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“…The GF of the honey samples diminish in accordance with the decrease in the samples' degree of crystallinity, indicating that the samples crystallites work as physical crosslinking points. The addition of the natural polymers, as well as the addition of honey, diminishes the gels' degree of crystallinity, diminishing the gels' GF [63,64] .…”

Section: In Vitro Analysismentioning

confidence: 99%

Layered cryogels laden with Brazilian honey intended for wound care

Santos

Pereira

et al. 2020

Polímeros

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“…When PVA is used in a drug carrier, it exhibits sustained-release properties due to its macromolecular swelling properties. Sustained-release drugs can reduce dosing frequency and improve patients' compliance, especially children and elderly patients [46][47][48][49].…”

Section: Introductionmentioning

confidence: 99%

Preparation of amphiphilic magnetic polyvinyl alcohol targeted drug carrier and drug delivery research

Wang

Shi

Sun³

et al. 2020

Designed Monomers and Polymers

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Currently, magnetic applications have great potential for development in the field of drug carriers. In this paper, Fe 3 O 4-PVA@SH, an amphiphilic magnetically targeting drug carrier, was prepared by using Fe 3 O 4 and PVA with thiohydrazide-iminopropyltriethoxysilane(TIPTS). The loading capacity of Fe 3 O 4-PVA@SH on Aspirin and the drug release kinetics of loaded drugs were studied. The obtained Fe 3 O 4-PVA@SH exhibits excellent drug release properties in simulating the human body fluid environment (pH 7.2). Since magnetically targeting drug carriers are readily available and have excellent biocompatibility and the characteristics of drug release. This work's development, preparing amphiphilic magnetically targeting drug carriers in drug delivery and other fields, has great significance.

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Radiation synthesis and drug delivery properties of interpenetrating networks (IPNs) based on poly(vinyl alcohol)/ methylcellulose blend hydrogels

Cited by 42 publications

References 29 publications

Studies on Preparation and Characterization of Blend Polymers for Hydrogels Synthesis and Use for Protein Release

Studies on Preparation and Characterization of Blend Polymers for Hydrogels Synthesis and Use for Protein Release

Layered cryogels laden with Brazilian honey intended for wound care

Preparation of amphiphilic magnetic polyvinyl alcohol targeted drug carrier and drug delivery research

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