Radical Hysterectomy for Recurrent Carcinoma of the Uterine Cervix after Radiotherapy

Coleman, Robert L.; Keeney, Elden D.; Freedman, Ralph S.; Burke, Thomas W.; Eifel, Patricia J.; Rutledge, Felix N.

doi:10.1006/gyno.1994.1242

Cited by 73 publications

(56 citation statements)

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“…Coleman et al (1994) reported that all five patients with positive nodes died of cancer, whereas 14 of 34 patients (41.2%) with negative nodes died of cancer (P ¼ 0.02). Maneo et al, (1999) identified six node-positive patients in their series, and five experienced recurrence, whereas half of 28 nodenegative patients experienced recurrence.…”

Section: Discussionmentioning

confidence: 99%

“…The utility of radical hysterectomy, a more conservative procedure, has been reported, but it also has a high rate of complications. Coleman et al (1994) evaluated the utility of radical hysterectomy (chiefly type III hysterectomy) including pelvic lymphadenectomy in 50 patients with persistent or recurrent cervical cancer after primary radiation therapy. The 5-and 10-year survival rates for all cases was 72 and 60%, but severe postoperative complications (grade III or higher) occurred in 42% of the patients, along with one postoperative death because of sepsis.…”

Section: Discussionmentioning

confidence: 99%

“…Coleman et al (1994) reported that tumour size at surgery is significantly associated with survival. The 5-year survival rate for the 12 of 44 patients (27.3%) with lesion diameter less than 2 cm was 90% compared with 64% in patients with larger lesions (Po0.01).…”

Section: Discussionmentioning

confidence: 99%

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Adjuvant hysterectomy for treatment of residual disease in patients with cervical cancer treated with radiation therapy

et al. 2008

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The objective of this retrospective study was to determine the efficacy of adjuvant hysterectomy for treatment of residual disease in cervical carcinoma treated with radiation therapy. Between 1971 and 1996, 1590 patients with carcinoma of the uterine cervix (stages I -IIIb) were treated with radiation therapy. Three months after completion of radiation therapy, the status of local control was investigated, and total abdominal hysterectomy was performed in cases in which central residual disease existed in the cervix. Of the 1590 patients, residual disease was identified in 162 patients. Among these patients, 35 showed an absence of distant metastasis or lateral parametrial invasion and underwent hysterectomy. The overall 5-and 10-year survival rates for these patients were 68.6 and 65.7%, respectively. There was no significant difference in survival between patients with squamous cell carcinoma and those with non-squamous cell carcinoma or between patients with stage I/II carcinoma and those with stage III carcinoma. With respect to treatment-related morbidity, five (14.3%) patients suffered grade III or IV complications after hysterectomy. Adjuvant hysterectomy is an effective addition to radiation therapy in the treatment of cervical cancer, even in patients with stage III disease and in those with non-squamous cell carcinoma.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Adjuvant hysterectomy for treatment of residual disease in patients with cervical cancer treated with radiation therapy

et al. 2008

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“…Seven case series [100][101][102][103][104][105][106] gave information on radical hysterectomy (Table 48). They were published between 1965 and 1999 and were mostly from the USA, Canada and the European Union (Italy and Denmark).…”

Section: Radical Hysterectomy Population Characteristicsmentioning

confidence: 99%

“…In five studies, 100,101,[103][104][105] radical hysterectomy was conducted as salvage surgery with curative intent. Tupper 106 described Wertheim's operation, and in Ibsen et al 102 both Wertheim's operation and pelvic exenteration (which could be total, anterior or posterior) were combined with pelvic lymph node dissection.…”

Section: Radical Hysterectomy Interventionmentioning

confidence: 99%

Positron emission tomography/computerised tomography imaging in detecting and managing recurrent cervical cancer: systematic review of evidence, elicitation of subjective probabilities and economic modelling

Meads

Auguste²,

Davenport³

et al. 2013

Health Technol Assess

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Reports are published in Health Technology Assessment (HTA) if (1) they have resulted from work for the HTA programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors.Reviews in Health Technology Assessment are termed 'systematic' when the account of the search appraisal and synthesis methods (to minimise biases and random errors) would, in theory, permit the replication of the review by others.

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Cervical Cancer

Klobocista

Einstein

Runowicz

2018

The American Cancer Society's Oncology in Practice

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Radical Hysterectomy for Recurrent Carcinoma of the Uterine Cervix after Radiotherapy

Cited by 73 publications

References 0 publications

Adjuvant hysterectomy for treatment of residual disease in patients with cervical cancer treated with radiation therapy

Adjuvant hysterectomy for treatment of residual disease in patients with cervical cancer treated with radiation therapy

Positron emission tomography/computerised tomography imaging in detecting and managing recurrent cervical cancer: systematic review of evidence, elicitation of subjective probabilities and economic modelling

Cervical Cancer

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