1991
DOI: 10.1016/s0022-5347(17)37725-x
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Radical Prostatectomy For Localized Prostatic Carcinoma in the Renal Transplant Patient

Abstract: Three renal transplant patients had prostatic carcinoma after transurethral prostatectomy at 2 weeks, 2 months and 12 years following transplantation. One patient had stage A1 disease, while 2 had stage A2 prostatic carcinoma. All patients underwent radical retropubic prostatectomy and pelvic lymph node dissection. All patients had residual cancer in the radical prostatectomy specimen but none had nodal or capsular involvement. The surgical technique and rationale for management are discussed.

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Cited by 31 publications
(21 citation statements)
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“…We did not find it necessary to intubate the transplanted ureter via cystoscopy at the beginning of surgery for better appreciation of its course, as recommended in early reports. 3,4 The reported experience of radiotherapy as primary therapy for localized prostate cancer in renal transplant patients is limited to a series of eight patients from France. 17 All patients received three-dimensional conformal therapy that comprised a nine-field arrangement delivering 70 Gy in 2-Gy fractions, with 18-MV photon beams.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…We did not find it necessary to intubate the transplanted ureter via cystoscopy at the beginning of surgery for better appreciation of its course, as recommended in early reports. 3,4 The reported experience of radiotherapy as primary therapy for localized prostate cancer in renal transplant patients is limited to a series of eight patients from France. 17 All patients received three-dimensional conformal therapy that comprised a nine-field arrangement delivering 70 Gy in 2-Gy fractions, with 18-MV photon beams.…”
Section: Discussionmentioning
confidence: 99%
“…While there have been previous reports of this surgery being performed through the open retropubic and perineal approaches [3][4][5][6] as well as the laparoscopic transperitoneal approach, 7,8 there is to date no reported experience of radical prostatectomy with the da Vinci robotic platform (Intuitive, Sunnyvale, CA) in this patient subset. We report a case study describing our experience of robotassisted laparoscopic radical prostatectomy in such a patient.…”
Section: Introductionmentioning
confidence: 99%
“…Alternatively, the EP approach is advantageous particularly in RTRs, providing direct access to the Retzius space without an increased risk of injury to the graft ureter during bladder take down. Furthermore, intubation of the transplanted ureter via cystoscopy at the beginning of surgery as recommended in early reports 8,9 is not required. While external beam radiotherapy remains an alternative treatment in patients with localized prostate cancer, it is not the treatment of choice in transplant patients, with only a 50% disease-free rate at 5 years.…”
Section: Discussionmentioning
confidence: 99%
“…7 Radical prostatectomy (RP) remains the treatment of choice for patients seeking surgical cure. Radical prostatectomy performed via the open retropubic, perineal 811 and laparoscopic approaches 1214 have been reported in RTRs. To date, only one case has been reported in the literature of a robotic prostatectomy in a transplant patient performed using a transperitoneal approach.…”
Section: Introductionmentioning
confidence: 99%
“…Radiation therapy is not advisable, as a total dose of 6,000 rads would have to be given and there is potential for damaging the transplanted kidney due to radiation scatter [7], The technique of radical prostatectomy for localised prostatic cancer in such patients has been de scribed, and the incidence of stage A prostatic malignancy in renal transplant patients appears to be higher than that 168 Srinivas/Deshmukh/Shah/Kapadia Radical Cystectomy for Squamous Bladder Cancer in Renal Transplant in the general population [8]. However, since bladder can cer is much rarer, even leading cancer centers have very limited experience in dealing with this problem [Sogani, P.C., Whitmore, W.F.…”
Section: Discussionmentioning
confidence: 99%