Radical vaginal trachelectomy vs. radical hysterectomy for small early stage cervical cancer: A matched case–control study

Beiner, Mario; Hauspy, Jan; Rosen, Barry P.; Murphy, Joan; Laframboise, S.; Nofech‐Mozes, Sharon; Ismiil, Nadia; Rasty, Golnar; Khalifa, Mahmoud A.; Covens, Allan

doi:10.1016/j.ygyno.2008.04.027

Cited by 106 publications

(68 citation statements)

References 21 publications

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“…The number of obtained pregnancies was consistent with our patients' desire for postoperative fertility. From this point of view, the data obtained in this study (15.7 %) were similar to the data in literature [3,28].…”

Section: Discussionsupporting

confidence: 91%

Radical Vaginal Trachelectomy with Laparoscopic Pelvic Lymphadenectomy for Fertility Preservation in Young Women with Early-Stage Cervical Cancer

Brătilă

Coroleucă³

2015

Indian J Surg

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The primary objective of this study was to describe our experience with the conservative treatment of early-stage cervical cancer (stages IA1, IA2, and IB1) with radical vaginal trachelectomy (RVT) and laparoscopic pelvic lymphadenectomy. This retrospective observational case series included 36 patients with early cervical cancer. Radical trachelectomy and laparoscopic pelvic lymphadenectomy were performed as described by D. Dargent in 32 of these cases. Oncologic, reproductive, and obstetric outcomes were observed subsequently over a median period of 42 (24-96) weeks. A total of 32 RVTs were preformed with a mean operating time of 117±22.8 (77-167) minutes and an average blood loss of 486 mL (150-800 mL). All obtained resection margins were negative for cancer. Lymphovascular space invasion was noted in 11 (30.55 %) of the cases. No recurrences occurred during the study period. Seven (17.8 %) patients were able to become pregnant postoperatively, five of whom delivered healthy infants near term. Radical vaginal trachelectomy with laparoscopic pelvic lymphadenectomy appears to be a safe therapeutic option for fertility preservation in young women with early cervical cancer.

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Section: Discussionsupporting

confidence: 91%

Radical Vaginal Trachelectomy with Laparoscopic Pelvic Lymphadenectomy for Fertility Preservation in Young Women with Early-Stage Cervical Cancer

Brătilă

Coroleucă³

2015

Indian J Surg

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“…There is increasing evidence in the literature that radical trachelectomy is a viable option for young women with cervical cancer who wish to preserve their fertility [10,11]; however, the eligibility for this procedure is controversial. Additionally, the status of radical trachelectomy is not clear [3,4,12].…”

Section: Discussionmentioning

confidence: 99%

Questionnaire survey of the current status of radical trachelectomy in Japan

Sato

Aoki

Kobayashi³

et al. 2010

Int J Clin Oncol

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“…In women with early cervical cancer to preserve fertility, this operation is well established [53][54][55][56] and considered to be as safe with laparoscopic pelvic lymphadenectomy. The first report of a robotic radical trachelectomy for fertility sparing in stage Ib1 adenocarcinoma of the cervix was published by Person et al [57], who reported two cases of robotic radical trachelectomy and pelvic lymphadenectomy performed in two nullipaurous women with early cervical cancer.…”

Section: Radical Trachelectomymentioning

confidence: 99%

Robotic surgery in gynecologic oncology

et al. 2011

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The goal of this paper is to review the current data documenting the advantages of robotic surgery over open or laparoscopic surgery. The aim of this study is to compare the complications and perioperative outcome of robotic surgery with open and laparocopic surgery, in gynecologic oncology. The terms radical robotic or robot-assisted hysterectomy in PubMed search lead to 41 references. We excluded one review of literature, ten studies with benign and malignant cases, eight cases reports, one letter to the editor. We kept the prospective studies and comparative studies (total abdominal hysterectomy (TAH) vs. total robotic hysterectomy (TRH), total laparoscopic hysterectomy (TLH) vs. TRH or TAH vs. TRH vs. TLH). The results are separated for endometrial cancers, early cervical cancers, pelvic and paraaortic lymph node dissections, radical parametrectomy and trachelectomy, and pelvic exenteration. The literature on robotic-assisted radical hysterectomy supports its safety and feasibility for the surgical management of early cervical cancer and endometrial cancer. However, the results of a phase III randomized clinical trial testing the equivalence of outcomes after laparoscopic or robotic radical hysterectomy with abdominal radical hysterectomy are expected.

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Radical vaginal trachelectomy vs. radical hysterectomy for small early stage cervical cancer: A matched case–control study

Cited by 106 publications

References 21 publications

Radical Vaginal Trachelectomy with Laparoscopic Pelvic Lymphadenectomy for Fertility Preservation in Young Women with Early-Stage Cervical Cancer

Radical Vaginal Trachelectomy with Laparoscopic Pelvic Lymphadenectomy for Fertility Preservation in Young Women with Early-Stage Cervical Cancer

Questionnaire survey of the current status of radical trachelectomy in Japan

Robotic surgery in gynecologic oncology

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