Radio-induced bullous pemphigoid

Cabrera-Rodríguez, Joaquín J.; Muñoz-García, Julia L.; Rivero, J. Quirós; Carmona, F. Ropero; Kavadoy, Y. Ríos

doi:10.1007/s12094-010-0469-9

Cited by 7 publications

(5 citation statements)

References 17 publications

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“…Table 1 provides a summary of patients' profiles, cancer types, lesion characteristics, histology and immunopathology [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31]. …”

Section: Resultsmentioning

confidence: 99%

Relationship between Radiation Therapy and Bullous Pemphigoid

2014

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Background: Bullous pemphigoid (BP) is an autoimmune subepidermal blistering disease. Objective: To review the literature on radiation therapy (RT)-associated BP. Methods: A review of the English language literature on patients who developed BP during and up to 10 years post RT was performed. Results: 29 patients were reported. 25 (86.2%) were women, 84% of whom had received RT for breast cancer. Three patients were male (10.3%). Gender was not mentioned in 1 (3.4%). 72% developed BP post RT; 28% developed BP while undergoing RT. BP was initially localized to irradiated sites in 25 patients and to non-irradiated sites in 2 patients. Two patients presented with generalized disease. Disease control was reported in 12 patients, partial remission in 7 and complete remission in 5. Conclusion: The clinical profile, response to therapy and clinical outcome may indicate that RT-associated BP may be a specific subset of BP with a relatively benign course.

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Section: Resultsmentioning

confidence: 99%

Relationship between Radiation Therapy and Bullous Pemphigoid

2014

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“…4 RT is one of several physical agents including ultraviolet light, thermal burns and skin grafts that have been reported to induce BP in normal skin. 5 Radiation-induced bullous pemphigoid (RIBP) affects mainly women with breast carcinomas, [6][7][8] but it has been reported also with other cancers (vulva, cervix, lung and esophagus). 9 Mul et al, reported a large series of BP associated with radiotherapy.…”

Section: Discussionmentioning

confidence: 99%

Bullous pemphigoid development during the course of breast cancer: a radiation induced or a radiation recall dermatitis?

et al. 2020

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Background: Bullous pemphigoid (BP) is the most common autoimmune bullous disease, which is usually seen in older ages. Rarely, radiotherapy (RT) has been reported as a localised trigger factor for BP. Case: We present a case of a 64-year-old woman who underwent radical mastectomy and radiation therapy for breast cancer. Two months after the completion of RT with adjuvant Trastuzumab, a BP eruption developed in the irradiated area, spreading thereafter to other skin areas. The patient was treated with oral corticosteroids and the lesions evolved favourably. Conclusion: This case demonstrates a relatively benign skin reaction that could develop during the course of cancer treatment, which required co-management by oncologists, pathologists and dermatologists.

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“…There are numerous case reports on ABD and breast cancer including predominantly BP [20,[81][82][83][84][85] and PV [86,87] with well-documented BP-lesion induction with radiotherapy.…”

Section: Malignancies Associated With Abdmentioning

confidence: 99%