Radioactive seed localization is the preferred technique in nonpalpable breast cancer compared with wire-guided localization and radioguided occult lesion localization

Theunissen, Carla I.J.M.; Rust, Esther A.Z.; Edens, Mireille A.; Bandel, Caroline; Berg, Janneke G. van’t Ooster-van den; Jager, Piet L.; Noorda, Eva M.; Francken, Anne Brecht

doi:10.1097/mnm.0000000000000659

Cited by 18 publications

(20 citation statements)

References 21 publications

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“…Instead of localization method, the risk factors for reoperations were multifocality of the tumour, larger tumour size, EIC and smaller specimen weight. This is consistent with previous studies [11,13]. There were more multifocal tumours in the RSL group.…”

Section: Main Messagesupporting

confidence: 93%

“…There are only few previous studies reporting LR rates after BCS using ROLL or RSL. Theunissen et al [11] reported a LR rate of 6.6% in the ROLL group (median follow-up 51 months) and no recurrences in the RSL group (median follow-up 33 months). A recent study by Aljohani et al [19] reported a LR of only 0.3%, but the median follow-up time was just 37 months in the RSL group.…”

Section: Local Recurrencesmentioning

confidence: 98%

“…Neither did Donker et al [10], who compared ROLL and RSL after neoadjuvant treatment (ROLL 7% vs. RSL 8%). Theunissen et al [11] compared all WGL, ROLL and RSL and they found that RSL results in a higher negative surgical margin rate and lower reoperation rate.…”

Section: Reoperationsmentioning

confidence: 99%

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Resection Margins and Local Recurrences of Impalpable Breast Cancer: Comparison Between Radioguided Occult Lesion Localization (ROLL) and Radioactive Seed Localization (RSL)

Niinikoski

Hukkinen

Leidenius

et al. 2020

European Journal of Surgical Oncology

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The aim of this retrospective study is to compare surgical margins, reoperation rates and local recurrences after breast conserving surgery (BCS) using radioguided occult lesion localization (ROLL) or radioactive seed localization (RSL). Materials and methods: We reviewed 744 consecutive patients with impalpable primary invasive breast cancer who underwent BCS at Helsinki University Hospital between 2010 and 2012. ROLL was used in our unit until October 31st, 2011; from November 1st we changed localization method to RSL. Results: 318 patients underwent ROLL and 426 RSL. Patients in the RSL group had more often multifocal (p ¼ 0.013) tumours. No statistically significant differences were found regarding tumour size, specimen weight, histology or grade of tumours or lymph node status. 42 (5.6%) patients were reoperated because of insufficient margins, 13 (4.1%) in the ROLL group and 29 (6.8%) in the RSL group. The reoperation rate was not different between the groups either in the univariable analysis (p ¼ 0.112) or in the multivariable binary logistic regression analysis (p ¼ 0.204). Risk factors for reoperations were multifocality of the tumour (p < 0.001), extensive intraductal component (p < 0.001), larger tumour size (p ¼ 0.011), and smaller specimen weight (p ¼ 0.014). The median follow-up time in the ROLL group was 81 (8e94) months and 64 (3e73) months in the RSL group. The five-year local recurrence-free survival (LRFS) estimates for ROLL and RSL groups were 98.0% and 99.4%, respectively (log-rank test, p ¼ 0.323). Conclusion: Reoperation rates and LRFS were comparable for ROLL and RSL in patients with impalpable breast cancer treated with BCS.

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Section: Main Messagesupporting

confidence: 93%

Section: Local Recurrencesmentioning

confidence: 98%

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Resection Margins and Local Recurrences of Impalpable Breast Cancer: Comparison Between Radioguided Occult Lesion Localization (ROLL) and Radioactive Seed Localization (RSL)

Niinikoski

Hukkinen

Leidenius

et al. 2020

European Journal of Surgical Oncology

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“…In cases in which ROLL was performed, the tumor-free margin rate was 82.5-90%. Re-excision rates range from 7.2% to 21% with RSL, 12% to 25% with WL and 10.9% with ROLL [7,[12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the nonradioactive inducible magnetic seed system Magseed for preoperative localization of nonpalpable breast lesions – initial clinical experience

Pieszko

Wichtowski

Cieciorowski

et al. 2020

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“…Current studies support that RSL and WL are comparable in outcomes related to volume of tissue removed and margin positivity . In this single institution experience, there were no differences in complication rate, re‐excision rate, margin positivity on final pathology or volume of tissue removed between RSL and WL.…”

Section: Discussionmentioning

confidence: 53%

Radioactive seed vs wire localization for nonpalpable breast lesions: A single institution review

et al. 2019

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The aim of this study was to compare wire localization (WL) and radioactive seed localization (RSL) for nonpalpable breast lesions with regard to margin status, re‐excision rate, procedure length, and complications related to localization. A retrospective review of the electronic health records at a single institution was performed. There was no difference in re‐excision rate, margin positivity, volume of tissue removed, and complication rate for RSL vs WL (P = 0.9934, P = 0.9934, P = 0.6645, and P = 0.4716 respectively). The only difference was a longer OR time, RSL = 104.408 minutes vs WL = 82.386 minutes. (P = 0.0163). RSL and WL are comparable techniques for localization of nonpalpable breast lesions.

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Radioactive seed localization is the preferred technique in nonpalpable breast cancer compared with wire-guided localization and radioguided occult lesion localization

Abstract: RSL results in a higher tumour-free margin rate in nonpalpable breast tumours compared with WGL and ROLL. Therefore, we prefer using RSL in nonpalpable breast tumours.

Cited by 18 publications

References 21 publications

Resection Margins and Local Recurrences of Impalpable Breast Cancer: Comparison Between Radioguided Occult Lesion Localization (ROLL) and Radioactive Seed Localization (RSL)

Resection Margins and Local Recurrences of Impalpable Breast Cancer: Comparison Between Radioguided Occult Lesion Localization (ROLL) and Radioactive Seed Localization (RSL)

Evaluation of the nonradioactive inducible magnetic seed system Magseed for preoperative localization of nonpalpable breast lesions – initial clinical experience

Radioactive seed vs wire localization for nonpalpable breast lesions: A single institution review

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