Radiofrequency ablation of liver metastasis from ovarian adenocarcinoma: case report and literature review

Bojalian, Michael O; Machado, Gustavo R.; Swensen, Ron E.; Reeves, Mark E.

doi:10.1016/j.ygyno.2004.01.041

Cited by 23 publications

(8 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Consequently, it is important that patients with GCT should be followed up regularly, even if the disease-free interval is long, and that adjuvant treatments may be reserved for patients with large residual or inoperable tumors. The literature on GCTs commonly advocates the use of radiofrequency ablation for hepatic metastases from GCT ( 9 – 11 ). Historically, surgical resection of liver metastases for GCT was performed merely as a palliative procedure, and not as a planned intervention, even though it resulted in a significant increase in disease-free survival ( 6 ).…”

Section: Discussionmentioning

confidence: 99%

Metastasis of the liver with a granulosa cell tumor of the ovary: A case report

Zhou

Hou

et al. 2014

Oncology Letters

View full text Add to dashboard Cite

The present study describes the case of a 62 year-old female patient with a metastatic tumor in the right hemi-liver of >25 cm in diameter, who presented to The Affiliated Hospital of Guilin Medical University (Guangxi, China) with acute abdominal pain and severe malnutrition. Radical surgery was performed to remove the tumor by open surgery. A biopsy was not performed prior to the surgery, so the tumor was diagnosed as end-stage primary liver cancer (PLC) based solely on the character and appearance of the tumor on computed tomography prior to surgery. However, subsequent to the surgery, upon analysis by the Department of Pathology, the mass was identified as an ovarian granulosa cell tumor (GCT). These tumors occur rarely, representing only 2–3% of all ovarian tumors, and are well known for late recurrences, with an incidence of 25–30%. As metastasis of the liver with GCT is extremely rare and the data available on the subject is limited by the small number of studies, and due to the absence of a biopsy report prior to surgery, the patient was initially misdiagnosed with PLC. However, despite this misdiagnosis, a good result was obtained, as the patient was later diagnosed with GCT following a detailed pathological examination and was treated with rational therapy. The performance status and quality of life were significantly improved, and the patient remains disease-free at one year post-surgery.

show abstract

Section: Discussionmentioning

confidence: 99%

Metastasis of the liver with a granulosa cell tumor of the ovary: A case report

Zhou

Hou

et al. 2014

Oncology Letters

View full text Add to dashboard Cite

show abstract

“…Radiofrequency ablation (RFA) provides an effective complement to hepatic surgery in OCLM patients with deep foci location and large tumor number. Till now, few numbers of cases reports showed the role of RFA in OCLM (49)(50)(51). RFA, as a local adjuvant therapy for OCLM, is feasible and effective.…”

Section: Non-surgical Treatmentmentioning

confidence: 99%

Surgical treatment of ovarian cancer liver metastasis

Wang

Zhou

Zhang

et al. 2019

Hepatobiliary Surg. Nutr

View full text Add to dashboard Cite

In addition to hepatocellular carcinoma, metastatic liver cancer (MLC) is another focus of hepatic surgeon. Good outcome of patients with liver metastasis (LM) from colorectal cancer or neuroendocrine tumor have been achieved. Ovarian cancer liver metastasis (OCLM) has its unique oncological characteristics and a variety of metastasis patterns, which brings a challenge to hepatic surgeon. Hepatic surgeons hold different views and techniques from gynecologists, which makes differences in the evaluation and treatment of the disease. We reviewed recent studies and, in combination with our own clinical experience, attempted to introduce the progress of surgical treatment of liver metastases from OC. In our experience, both preoperative imaging and surgical procedures are based on the assurance of R0 resection. R0 cytoreductive surgery (CRS) is the most favorable determinant for the prognosis of OC patients, and R0 liver resection (LR) is a component of R0 CRS. Gynecologists and hepatic surgeons should do their own preoperative and intraoperative evaluation for the extrahepatic and intrahepatic metastasis respectively. During the operation, regardless of the miliary nodules dissemination between the right hemidiaphragm and liver capsule, liver parenchymal infiltration (LPI) or liver parenchymal metastasis (LPM), 1-2 cm resection margin should be emphasized. For patients with liver portal lymph node metastasis (LPLNM), hepatic portal skeletonization should be performed, rather than portal lymph node dissection. The operation should be as radical as possible to ensure the patients to achieve good prognosis.

show abstract

“…A variety of local, intratumoral therapies have been developed to provide advantages over surgery and chemo-radiation, that include minimal invasiveness, minimal side effects, and shorter hospitalizations. [1][2][3][4] These therapies are based on different physical mechanisms and ablation techniques including microwave, [5][6][7] focused ultrasound, [8][9][10] radiofrequency, 11,12 and cryoablation [13][14][15] therapies. The disadvantages of these therapies include limited specificity, limited delivery, and tumor recurrence.…”

Section: Introductionmentioning

confidence: 99%

A histological evaluation and in vivo assessment of intratumoral near infrared photothermal nanotherapy-induced tumor regression

Green¹,

Crockett²,

Martyshkin³

et al. 2014

IJN

View full text Add to dashboard Cite

Purpose Nanoparticle (NP)-enabled near infrared (NIR) photothermal therapy has realized limited success in in vivo studies as a potential localized cancer therapy. This is primarily due to a lack of successful methods that can prevent NP uptake by the reticuloendothelial system, especially the liver and kidney, and deliver sufficient quantities of intravenously injected NPs to the tumor site. Histological evaluation of photothermal therapy-induced tumor regression is also neglected in the current literature. This report demonstrates and histologically evaluates the in vivo potential of NIR photothermal therapy by circumventing the challenges of intravenous NP delivery and tumor targeting found in other photothermal therapy studies. Methods Subcutaneous Cal 27 squamous cell carcinoma xenografts received photothermal nanotherapy treatments, radial injections of polyethylene glycol (PEG)-ylated gold nanorods and one NIR 785 nm laser irradiation for 10 minutes at 9.5 W/cm 2 . Tumor response was measured for 10–15 days, gross changes in tumor size were evaluated, and the remaining tumors or scar tissues were excised and histologically analyzed. Results The single treatment of intratumoral nanorod injections followed by a 10 minute NIR laser treatment also known as photothermal nanotherapy, resulted in ~100% tumor regression in ~90% of treated tumors, which was statistically significant in a comparison to the average of all three control groups over time ( P <0.01). Conclusion Photothermal nanotherapy, or intratumoral nanorod injections followed by NIR laser irradiation of tumors and tumor margins, demonstrate the potential of NIR photothermal therapy as a viable localized treatment approach for primary and early stage tumors, and prevents NP uptake by the reticuloendothelial system.

show abstract

Radiofrequency ablation of liver metastasis from ovarian adenocarcinoma: case report and literature review

Cited by 23 publications

References 14 publications

Metastasis of the liver with a granulosa cell tumor of the ovary: A case report

Metastasis of the liver with a granulosa cell tumor of the ovary: A case report

Surgical treatment of ovarian cancer liver metastasis

A histological evaluation and in vivo assessment of intratumoral near infrared photothermal nanotherapy-induced tumor regression

Contact Info

Product

Resources

About