Radiofrequency Ablation of Osteoma Osteoide: A Finite Element Study

Irastorza, Ramiro M.; Trujillo, Macarena; Martel, José; Berjano, Enrique

doi:10.1007/978-3-319-13117-7_218

Cited by 3 publications

(5 citation statements)

References 14 publications

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“…It has been suggested that the presence of cortical bone during RFA could play the role of a thermal insulator and hence grant protection to the adjacent soft tissues [7][8][9]. We have already observed this performance in a previous modeling study [10], which could be explained by the lower electrical conductivity of the cortical bone than the surrounding tissues.…”

Section: Introductionmentioning

confidence: 73%

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Computer modelling of RF ablation in cortical osteoid osteoma: Assessment of the insulating effect of the reactive zone

Irastorza

Trujillo

Martel

et al. 2016

International Journal of Hyperthermia

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2 AbstractPurpose: To study by computer simulations the insulating role of the reactive zone surrounding a cortical osteoid osteoma (OO) in terms of electrical and thermal performance during radiofrequency ablation (RFA). Material and methods:We modeled a cortical OO consisting of a nidus (10 mm diameter) enclosed by a reactive zone. The OO is near a layer of cortical bone 1.5 mm thick. Trabecular bone partially surrounds the OO and there is muscle around the cortical bone layer. We modeled RF ablations with a non-cooled-tip 17G needle electrode (300 s duration and 90ºC target temperature). Sensitivity analyses were conducted assuming a reactive zone electrical conductivity value (σ rz ) within the limits of the cortical and trabecular bone, i.e. 0.02 S/m and 0.087 S/m, respectively. In this way we were really modeling the different degrees of osteosclerosis associated with the reactive zone. Results:The presence of the reactive zone drastically reduces the maximum temperature reached outside it. The temperature drop is proportional to the thickness of the reactive zone: from 68ºC when it is absent to 44ºC when it is 7.5 mm thick. Higher nidus conductivity values (σ n ) implied higher temperatures, while lower temperatures meant higher σ rz values. Changing σ rz from 0.02 S/m to 0.087 S/m reduced lesion diameters from 2.4 cm to 1.8 cm. Conclusions:The computer results suggest that the reactive zone plays the role of insulator in terms of reducing the temperature in the surrounding area.

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Section: Introductionmentioning

confidence: 73%

“…Table 1 shows the values of the physical characteristics of the materials used in the model [22,23]. The thermal conductivity and specific heat of cortical bone and muscle were taken from a previous sensitivity analysis [10]. A change in σ with temperature was considered of +1.5 %/°C (with an abrupt drop when temperature reaches 100°C)…”

mentioning

confidence: 99%

Computer modelling of RF ablation in cortical osteoid osteoma: Assessment of the insulating effect of the reactive zone

Irastorza

Trujillo

Martel

et al. 2016

International Journal of Hyperthermia

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“…20 Although this is model dependent, a good agreement was found by setting K p at 1.15 V/K and K i at 0.06 V/K/s. 21 For most of the model, the Trujillo and Berjano 22 model propositions for biological tissues, temperature-dependent parameters of electrical conductivity, thermal conductivity, and apparent heat capacity were used as reference.…”

Section: Equations Governing Radiofrequency Ablationmentioning

confidence: 99%

“…Of the three Bitsch et al models, the one with a 3 mm lamella thickness was chosen arbitrarily here, but our model was compared against all their configurations. For a more detailed explanation of the ex-vivo experiments and the assumptions to replicate them, please refer to Bitsch et al 20 and Irastorza et al, 21 respectively.…”

Section: Validation Of the Modelmentioning

confidence: 99%

“…Our model is based on the computer model by Irastorza et al, 21 who modeled RFA of OO and compared their results to the ex-vivo experiments by Bitsch et al 21 To validate our model, the Irastorza et al model was replicated as best as possible and the results from our model were compared against their results and against the ex-vivo experiment by Bitsch et al The values from their studies were obtained with WebPlotDigitizer 34 and compared against the results from our simulations.…”

Section: Validation Of the Modelmentioning

confidence: 99%

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Effects of control temperature, ablation time, and background tissue in radiofrequency ablation of osteoid osteoma: A computer modeling study

Loya

Hijlkema

Cornelissen

et al. 2021

Numer Methods Biomed Eng

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To study the effects of the control temperature, ablation time, and the background tissue surrounding the tumor on the size of the ablation zone on radiofrequency ablation (RFA) of osteoid osteoma (OO). Finite element models of non‐cooled temperature‐controlled RFA of typical OOs were developed to determine the resulting ablation radius at control temperatures of 70, 80, and 90°C. Three different geometries were used, mimicking common cases of OO. The ablation radius was obtained by using the Arrhenius equation to determine cell viability. Ablation radii were larger for higher temperatures and also increased with time. All geometries and control temperatures tested had ablation radii larger than the tumor. The ablation radius developed rapidly in the first few minutes for all geometries and control temperatures tested, developing slowly towards the end of the ablation. Resistive heating and the temperature distribution showed differences depending on background tissue properties, resulting in differences in the ablation radius on each geometry. The ablation radius has a clear dependency not only on the properties of the tumor but also on the background tissue. Lower background tissue's electrical conductivity and blood perfusion rates seem to result in larger ablation zones. The differences observed between the different geometries suggest the need for patient‐specific planning, as the anatomical variations could cause significantly different outcomes where models like the one here presented could help to guarantee safe and successful tumor ablations.

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Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy

et al. 2022

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Background Radiofrequency ablation (RFA) is a minimally invasive technique used for the treatment of neoplasms, with a growing interest in the treatment of bone tumours. However, the lack of data concerning the size of the resulting ablation zones in RFA of bone tumours makes prospective planning challenging, needed for safe and effective treatment. Methods Using retrospective computed tomography and magnetic resonance imaging data from patients treated with RFA of atypical cartilaginous tumours (ACTs), the bone, tumours, and final position of the RFA electrode were segmented from the medical images and used in finite element models to simulate RFA. Tissue parameters were optimised, and boundary conditions were defined to mimic the clinical scenario. The resulting ablation diameters from postoperative images were then measured and compared to the ones from the simulations, and the error between them was calculated. Results Seven cases had all the information required to create the finite element models. The resulting median error (in all three directions) was -1 mm, with interquartile ranges from -3 to 3 mm. The three-dimensional models showed that the thermal damage concentrates close to the cortical wall in the first minutes and then becomes more evenly distributed. Conclusions Computer simulations can predict the ablation diameters with acceptable accuracy and may thus be utilised for patient planning. This could allow interventional radiologists to accurately define the time, electrode length, and position required to treat ACTs with RFA and make adjustments as needed to guarantee total tumour destruction while sparing as much healthy tissue as possible.

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Radiofrequency Ablation of Osteoma Osteoide: A Finite Element Study

Cited by 3 publications

References 14 publications

Computer modelling of RF ablation in cortical osteoid osteoma: Assessment of the insulating effect of the reactive zone

Computer modelling of RF ablation in cortical osteoid osteoma: Assessment of the insulating effect of the reactive zone

Effects of control temperature, ablation time, and background tissue in radiofrequency ablation of osteoid osteoma: A computer modeling study

Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy

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