Radiofrequency Ablation of Thoracic Lesions: Part 2, Initial Clinical Experience—Technical and Multidisciplinary Considerations in 30 Patients

vanSonnenberg, Eric; Shankar, Sridhar; Morrison, Paul R.; Nair, Rashmi; Silverman, Stuart G.; Jaklitsch, Michael T.; Liu, Franklin; Cheung, Lawrence; Tuncalı, Kemal; Skarin, Arthur T.; Sugarbaker, David J.

doi:10.2214/ajr.184.2.01840381

Cited by 109 publications

(58 citation statements)

References 24 publications

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“…Van Sonnenberg et al report using intercostal and paravertebral nerve blocks with a long-acting local anesthetic to prevent postprocedural discomfort and pain. 9 There are also reports of cryoanalgesia effect in the intercostals nerves during cryoablation procedures. 10 During ablation procedures, patients undergo monitoring with continuous pulse oximetry, electrocardiography, and measurement of blood pressure every 5 minutes.…”

Section: Methodsmentioning

confidence: 99%

Current Status of Thermal Ablation Treatments for Lung Malignancies

Dupuy

Shulman²

2010

Semin intervent Radiol

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About 75% of lung cancer patients are not surgical candidates, either due to advanced disease or medical comorbidities. Furthermore, conventional treatments that can be offered to these patients are beneficial only to a small percentage of them. Thermal ablation is a minimally invasive treatment that is commonly used in this group of patients, and which has shown promising results. Currently, the most widely used ablation techniques in the treatment of lung malignancies are radiofrequency ablation (RFA), microwave ablation, and cryoablation. Although the most studied technique is RFA, recent studies with microwave ablation and cryoablation have shown some advantages over RFA. This article reviews the application of thermal ablation in the thorax, including patient selection, basic aspects of procedure technique, imaging follow-up, treatment outcomes, and comparison of ablation techniques.

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Section: Methodsmentioning

confidence: 99%

Current Status of Thermal Ablation Treatments for Lung Malignancies

Dupuy

Shulman²

2010

Semin intervent Radiol

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“…After preliminary studies on the electrochemical polarization of cancers, new percutaneous therapeutic modalities have emerged, including percutaneous brachytherapy (6) and thermal ablation of tumors by radiofrequency (RF) or other sources of energy (7). Thermal ablation is currently used to treat focal cardiologist (14,15). Bipolar systems having two active electrodes inserted into the lesion are now commercially available, overcoming the need for dispersive skin electrodes.…”

Section: Types Of Energymentioning

confidence: 99%

“…More uncommon indications are reported in the literature, including palliation of symptoms such as pain, cough or hemoptysis, recurrent disease in a radiation field, or tumor debulking (2,3,14,28,(31)(32)(33)(34) (Fig. 5).…”

Section: Indicationsmentioning

confidence: 99%

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Percutaneous ablation of malignant thoracic tumors

Ghaye

2013

Journal of the Belgian Society of Radiology

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Lung cancer is the leading cause of death related to cancer. Fifteen to thirty percent of patients with a localized lung cancer are actually inoperable as they present with poor general condition, limited cardiopulmonary function, or a too high surgical risk. Therefore, minimally invasive treatments are needed and percutaneous ablation seems an attractive option. Thermal ablation can be performed by delivering heat (radiofrequency, microwave, laser) or cold (cryotherapy) through a needle inserted into the tumor under CT guidance. The ideal lesion is less than 2 or 3 cm in diameter. Success of percutaneous thermal ablation appears to be close to those of surgery for localized lung cancer. Nevertheless studies are still needed to definitely assess the role of ablation compared to other emerging techniques, as stereo tactic radiotherapy as well as potential synergy with other treatments.

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“…Indications for palliative ablation include dyspnea, cough, hemoptysis or pain related to disease progression [73]. Remarkable reduction of pain, cough, hemoptysis and dyspnea is reported by several Authors [27,41,74,75].…”

Section: Radiological Criteriamentioning

confidence: 99%

Patient selection - clinical and imaging criteria - for percutaneous lung malignancies ablation: a single centre experience and a literature review

Carrafiello¹,

Cardim²,

Piacentino³

et al. 2012

J Cancer Ther Res

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Purpose: To settle the most important clinical and radiological selection criteria for percutaneous ablation in patients with pulmonary tumours. Materials and Methods:A retrospective analysis of pulmonary thermal ablations performed in our Centre with special "focus" on clinical and radiological selection criteria for thermal ablation. The criteria employed in our Centre were then compared with those of 24 studies chosen from Literature that fit the issue and described their patient selection criteria for lung tumours thermal ablation.Results: From May 2008 until May 2011, thermal ablation was indicated as an alternative to conventional treatment for 32 patients (20 males e 12 females) with NSCLC in different stages, with medium age of 71 years old (range 46 -82). Inoperability was a condition established for all patients, for their clinical conditions, especially poor lung function, for the disease extension, as a controlled metastasis, and/or for their diameter and localization, as lesions in proximity to heart, large vessels and trachea. Conclusion:Thermal ablation is a rational alternative for conventional therapy in an adequately selected group of patients. A randomized controlled study with a control group submitted to conventional therapies to define with precision the candidable patients to thermal ablative therapy would be necessary.

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Radiofrequency Ablation of Thoracic Lesions: Part 2, Initial Clinical Experience—Technical and Multidisciplinary Considerations in 30 Patients

Cited by 109 publications

References 24 publications

Current Status of Thermal Ablation Treatments for Lung Malignancies

Current Status of Thermal Ablation Treatments for Lung Malignancies

Percutaneous ablation of malignant thoracic tumors

Patient selection - clinical and imaging criteria - for percutaneous lung malignancies ablation: a single centre experience and a literature review

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