Radiofrequency renal denervation with mono-electrode and multi-electrode device for treatment in patient with uncontrolled hypertension: results of a 6-month follow-up

Agaeva, Regina A.; Агаевна, Агаева Регина; Данилов, Н. М.; Михайлович, Данилов Николай; Shchcelkova, Galina V.; Владимировна, Щелкова Галина; Matchin, Yu. G.; Георгиевич, Матчин Юрий; Чазова, И Е; Евгеньевна, Чазова Ирина

doi:10.26442/2075082x.2020.1.200077

Cited by 5 publications

(1 citation statement)

References 11 publications

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“…В настоящее время в России провели около 200 процедур РДН различными устройствами II поколения. В июне 2020 г. опубликованы данные 32 пациентов, которым проведена процедура РДН с применением Symplicity Spyral [40]. Результаты продемонстрировали выраженный гипотензивный эффект через 6 мес наблюдения как по данным клинического контроля, так и по данным СМАД.…”

Section: опыт проведения рдн в рфunclassified

Russian medical society on arterial hypertension (RMSAH) Consensus of Experts on the use of radiofrequency denervation of the renal arteries in patients with arterial hypertension

et al. 2021

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Hyperactivity of the sympathetic nervous system is one of the basic mechanisms in the development of arterial hypertension (AH). Transcatheter renal artery denervation is aimed to destroy the renal sympathetic afferent and efferent nerves to achieve a sustained reduction in blood pressure. Since 2017, all II generation studies have demonstrated that sympathetic denervation provides clinically significant BP reduction. Russian Medical Society for Arterial Hypertension (RMSAH) experts consider SD as a possible addition to the antihypertensive strategy in patients with uncontrolled AH and recommend denervation of the renal arteries in registers and clinical trials. On the basis of existing randomized clinical trials, as well as the experience of radiofrequency denervation in Russia, the experts of RMSAH present a consensus and view of the current situation in the field of renal denervation.

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Section: опыт проведения рдн в рфunclassified

Russian medical society on arterial hypertension (RMSAH) Consensus of Experts on the use of radiofrequency denervation of the renal arteries in patients with arterial hypertension

et al. 2021

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Renal denervation may attenuate the severity of MRI-signs of vascular wall damage in diabetic patients with resistant hypertension due to the anti-inflammatory effect

et al. 2020

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Predictors of the preservation of renal parenchyma volume after renal denervation in patients with resistant hypertension according to magnetic resonance imaging

Ryumshina,

Zyubanova,

Musatova

et al. 2023

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Objective. To define the indicators that allow predicting the preservation of the volume of the renal parenchyma according to magnetic resonance imaging (MRI) data in resistant arterial hypertension (RHT) one year after renal denervation (RDN).Design and methods. The study included 66 patients with RHT (average age 57,6 ± 9,4 years). Anamnesis, renal MRI data, results of the 24-h ambulatory blood pressure (BP) monitoring, lipid profile, serum markers of renal dysfunction initial and 1 year after RDN were analyzed. The group with preserved renal parenchyma volume consisted of 30 patients; the group with reduced renal parenchyma volume included 36 patients. Renal MRI was performed with the use of a 1,5 T device. Kidney volumes were calculated by the ellipsoid formula (Total kidney volume, TKV) and by the modified ellipsoid formula — the volume of the cortical layer (Total Cortex Volume, TCortexV). In addition, indices of renal parenchyma volumes adjusted for height are proposed for analysis: htTKV = TKV/height2,7 and htTCortexV = TCortexV/height2,7.Results. Univariate logistic regression analysis showed that statistically significant predictors of the preservation of renal parenchyma volume 1 year after RDN are lower initial values of htTKV (p = 0,02) and htTCortexV (p = 0,033), absence of diabetes mellitus type 2 (p = 0,03), lower pulse BP (p = 0,013) and younger age at the time of RDN (p = 0,03). Multivariate regression analysis, taking into account all variables, showed that the logistic regression model included the following independent predictors of renal parenchyma volume retention 1 year after RDN: age at the time of RDN (odds ratio (OR) 1,06 (confidence interval (CI) 0,99–1,13)), absence of chronic kidney disease (CKD) (OR 0,08 (CI 0,02–0,46)), htTCortexV (OR 0,89 (CI 0,82–0,96)), pulse BP (OR 0,94 (CI 0,91–0,99)), body mass index (BMI) (OR 0,95 (CI 0,85–1,07)).Conclusions. Predictors of the preservation of renal parenchyma volume include: lower age at the time of RDN, absence of CKD, lower values of htTCortexV calculated from MRI data, lower values of pulse blood pressure and BMI. These parameters can be used for the selection of patients with RHT for the RDN.

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Radiofrequency renal denervation with mono-electrode and multi-electrode device for treatment in patient with uncontrolled hypertension: results of a 6-month follow-up

Cited by 5 publications

References 11 publications

Russian medical society on arterial hypertension (RMSAH) Consensus of Experts on the use of radiofrequency denervation of the renal arteries in patients with arterial hypertension

Russian medical society on arterial hypertension (RMSAH) Consensus of Experts on the use of radiofrequency denervation of the renal arteries in patients with arterial hypertension

Renal denervation may attenuate the severity of MRI-signs of vascular wall damage in diabetic patients with resistant hypertension due to the anti-inflammatory effect

Predictors of the preservation of renal parenchyma volume after renal denervation in patients with resistant hypertension according to magnetic resonance imaging

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