“…Heating energy can be applied by external means or internally via interstitial, intraluminal or intracavitary approaches. Numerous clinical examples of non-oncological high-temperature thermal treatments abound, including treatment of prostatic hyperplasia 1,2 , cardiac arrythmias 3,4 , uterine fibroids 5,6 , low back pain 7 , reduction of upper palate and turbinates to reduce snoring 8,9 , stabilization of skeletal joints 10,11 and cosmesis such as dermal tightening 12,13 . High temperature therapy or thermal ablation is also being applied to treat localized cancerous tumours in sites such as brain 14,15 , liver [16][17][18] , kidney 19 , lung 20 , breast 5 and bone 21 .…”