Radiographic evaluation of malignant fibrous histiocytoma affecting maxillary alveolar bone: A report of 2 cases

Malignant fibrous histiocytoma of maxillary alveolar ridge extending to the hard palate

“…[1,3,4,8,10] The majority of investigators have reported male predominance with a male: female ratio of 2:1. [1,3,4,8,10] However, contrary to this, Chen et al found female predominance with male: female ratio of 1:2. [2] In our case, it was a primary tumor reported in a female who was in her fifth decade.…”

“…[2] The differential diagnosis of MFH includes squamous cell carcinoma, malignant lymphoma, malignant giant cell tumor, and osteolytic osteosarcoma. [3] On conventional radiographs, MFH appears as an ill-defined, osteolytic lesion. [6] Park et al described advanced imaging findings of MFH.…”

“…[9] The extremities and the retroperitoneum are the most common locations for MFH. [2,3,5,6] Head and neck remains an uncommon location for MFH, as it accounts for only 3-10% of all cases. [1,6,8,10] In the head and neck region, the nasal cavity and paranasal sinuses are the most common sites from which subsequent involvement of maxillary alveolar bone can occur.…”

“…[1,6,8,10] In the head and neck region, the nasal cavity and paranasal sinuses are the most common sites from which subsequent involvement of maxillary alveolar bone can occur. [3,4,6] The oral cavity as such is a less common site for primary MFH and when involved, it mainly affects the jawbones. However, it can also occur in the buccal mucosa, lip, gingiva, tongue, alveolar ridge, and hard palate.…”

“…[2][3][4][5][6] O'Brian and Stout were the first to delineate MFH in 1964. [2][3][4][5][6] Later on, Kempson and Kyriakos described the histopathological features of MFH. [7] Apart from the soft-tissues, this tumor can occur in all other parts of the body, including bone.…”