Radiologic appearances of Brunner's gland adenoma: a case report

A case of Brunner's gland hyperplasia with features of duodenal cancer

“…1,2,6,7 Endoscopic pinching biopsy usually gives a negative result, because the tumor is almost entirely covered with thick intact duodenal mucosa in the biopsy sites, and the biopsy is often not deep enough to reach the submucosal tumor tissue. 8 Moreover, the present author previously reported gastric cancer mimicking submucosal tumor 9 and angiodysplasia. 10 Since a biopsy specimen taken from the former lesion did not show any histological features of malignancy, endoscopic mucosal resection (EMR) was performed to establish the correct diagnosis.…”

Brunner’s Gland Hyperplasia: A Rare Cause for Gastric Outlet Obstruction

“…Large polyps that may not be snared endoscopically are treated surgically. Since pinch biopsy of BGH has low sensitivity to detect the lesion [15], there have been reports of overtreating submucosal masses suspicious of gastric or pancreatic malignancy with procedures like duodenocephalopancreatectomy with surgical pathology report revealing BGH [21]. Such procedures, however, may be justified in cases where there is high suspicion of malignancy and lack of preoperative tissue diagnosis.…”

“…Diagnostically, a barium meal study may suggest a filling defect in the duodenal mucosa. Endoscopically, pedunculated or sessile polyps of variable sizes may be detected most commonly in the duodenal bulb [15]. It may also present as a submucosal mass on endoscopy arousing suspicion for malignancy [16].…”

Brunner’s gland hyperplasia: a rare case report

“…8 Since in the present case an endoscopic biopsy from the tumor did not show any histological features of malignancy, and CT features suggested the possibility of malignancy, surgery was planned, even though the frozen biopsy showed no evidence of malignancy, we decided to carry on with exploratory laparotomy and a circumscribed lesion of approximately 1.5cms found in the second part of duodenum, it was excised Heineke-Mickulicz pyloroplasty was done.…”