Radiologic Evaluation of Bone Loss at Implants with Biocide Coated Titanium Abutments: A Study in the Dog

Abstract

The objective of the present study is to evaluate bone loss at implant abutments coated with a soda-lime glass containing silver nanoparticles subjected to experimental peri-implantitis. Five beagle dogs were used in the experiments, 3 implants were installed in each quadrant of the mandibles. Glass/n-Ag coted abutments were connected to implant platform. Cotton floss ligatures were placed in a submarginal position around the abutment necks and the animals were subject to a diet which allowed plaque accumulation, and after 15 weeks the dogs were sacrificed. Radiographs of all implant sites were obtained at the beginning and at the end of the experimentally induced peri-implantitis. The radiographic examination indicated that significant amounts of additional bone loss occurred in implants without biocide coating, considering both absolute and relative values of bone loss. Percentages of additional bone loss observed in implants dressed with a biocide coated abutment were about 3 times lower (p<0.006 distal aspect; and p<0.031 at mesial aspect) than the control ones. Within the limits of the present study it seems promising the use of soda-lime glass/nAg coatings on abutments to prevent peri-implant diseases.

Evaluation in a Dog Model of Three Antimicrobial Glassy Coatings: Prevention of Bone Loss around Implants and Microbial Assessments

“…For a comparative purpose, a soda-lime glass containing silver nanoparticles is also evaluated. The efficacy of this kind of glass to prevent peri-implant diseases was pointed out in previous works [ 21 , 22 ]…”

Antibacterial nanosilver coated orthodontic bands with potential implications in dentistry

“…In another study nanosilver coating of implants is shown to reduce the risk of peri-implantitis18. In the antimicrobial activity test no growth inhibition was seen around the control and uncoated material, and a minimal growth inhibition was observed around the silver ion coated bands.…”

Current state‐of‐the‐art and future perspectives of the three main modern implant‐dentistry concerns: Aesthetic requirements, mechanical properties, and peri‐implantitis prevention

“…119 Implants with titanium abutments coated by a soda lime glass containing silver nanoparticles are capable of constraining the experimentally induced peri-implantitis bone loss. This particular coating decreases the total bone recession caused by induced periimplantitis, [120][121][122] but causes an initial time-limited gingival inflammation. 120,122 Silver nanoparticles deposited by anodic spark deposition in combination with a solution containing silicon, calcium, phosphorus, and sodium for a biomimetic coating on titanium substrates was able to reduce bacterial adhesion and provide osteointegrative properties.…”

“…This particular coating decreases the total bone recession caused by induced periimplantitis, [120][121][122] but causes an initial time-limited gingival inflammation. 120,122 Silver nanoparticles deposited by anodic spark deposition in combination with a solution containing silicon, calcium, phosphorus, and sodium for a biomimetic coating on titanium substrates was able to reduce bacterial adhesion and provide osteointegrative properties. 123 Besides silver, other inorganic agents, such as copper, 113,124 fluorine, 125,126 and zinc 15,124 have been introduced as potential antimicrobial agents in dental implant coatings.…”