Disclaimer The funding sources had no active role in collection of the data, writing and final approval of the manuscript. Conflict of interest Christophe M. Deroose reports fees for consulting or advisory roles with Ipsen, Novartis, Terumo and Advanced Accelerator Applications; participation in speakers' bureaus with Terumo and Advanced Accelerator Applications and travel, accommodations or expenses with General Electric and Terumo. Caroline Caramella reports honoraria from Pfizer, BMS, MSD, Astra-Zeneca and Roche. Laure Fournier reports research support from Philips, ArianaPharma, Evolucare and Invectys; honoraria or consulting fees from Novartis, Janssen and Sanofi and speaker fees from Novartis, Bayer, Janssen, Sanofi, Pfizer and GE Healthcare. Marion Smits reports honoraria paid to the institution for trial review by Parexel Ltd. and for lecturing by GE Healthcare.