Radiosurgical treatment of trigeminal neuralgia: evaluating quality of life and treatment outcomes

Petit, Joshua H.; Herman, Joseph M.; Nagda, S.; DiBiase, Steven J.; Chin, Lawrence S.

doi:10.1016/s0360-3016(03)00264-5

Cited by 119 publications

(60 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[4][5][6][12][13][14][15][30][31][32] The effect of the latency period after SRS in our study is comparable with the findings in previously reported series. 8,17,22,23,29,31 Interestingly, patients with previous surgery seem to be more frequently late responders to GKS than patients with no history of previous surgery. Our excellent and good outcome rates are comparable to those reported in previously published studies.…”

Section: Discussionmentioning

confidence: 99%

“…8,16 Numerous authors have reported on SRS with the GK, and outcome and complication rates have been variable. [1][2][3][4][5][6]8,[10][11][12][13][14][15][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32] The observed variation in success rates in the literature may be explained by the subjectivity of assessing pain (which is the most important outcome parameter in these studies), the multifactorial causes of TN (idiopathic or secondary to a pathological entity), the significantly varying stereotactic radiosurgical treatment protocols (different anatomical targets and different radiation doses), and the usage of illdefined and widely variable outcome assessment criteria.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Gamma Knife stereotactic radiosurgical treatment of idiopathic trigeminal neuralgia: long-term outcome and complications

Fountas¹,

Smith²,

Lee³

et al. 2007

FOC

View full text Add to dashboard Cite

Object Stereotactic radiosurgery (SRS) with the Gamma Knife (GK) is a rapidly emerging surgical modality in the management of medically refractory idiopathic trigeminal neuralgia (TN). The current study examines the long-term outcome in patients with drug-resistant idiopathic TN who underwent GK surgery at the authors‘ institution. Methods One hundred and six consecutive patients (38 men and 68 women) with proven medically refractory idiopathic TN were included in this retrospective study. Their ages were 41–82 years (mean 72.3 years). All patients underwent SRS with prescribed maximal radiation doses ranging from 70 to 85 Gy. Isocenters 1–3 were used and plugging was used selectively. The follow-up period was 12–72 months (mean 34.3 months). The patients were divided into 2 groups according to their history of previous surgery. Results The initial response rate in patients with no history of previous surgery was 92.9%; in those who had undergone previous surgery, the initial response rate was 85.7%. At the end of the 1st posttreatment year, an excellent outcome was achieved in 82.5% of patients who had not had previous surgery, and in 69.4% of those who had. The respective outcome rates for the 2nd posttreatment year were 78 and 63.5%, respectively. The most common complication was the development of persistent paresthesia, which occurred in 15.8% of patients with no previous surgery and 16.3% of those with previous surgery. Conclusions Stereotactic radiosurgery with the GK is a safe and effective treatment option for patients with medically refractory idiopathic TN.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Gamma Knife stereotactic radiosurgical treatment of idiopathic trigeminal neuralgia: long-term outcome and complications

Fountas¹,

Smith²,

Lee³

et al. 2007

FOC

View full text Add to dashboard Cite

show abstract

“…Other authors did not found influence of atypical neuralgia on pain improvement (Aubuchon, 2010;Petit, 2003;Pollock, 2002;Regís, 2009;Sheehan, 2005). No publications informing better results in patients with atypical facial pain were found.…”

Section: Pain Distributionmentioning

confidence: 96%

“…Han (Han, 2009), Sheehan (Sheehan, 2005), Regis (Regís, 2006) and Towk (Tawk, 2005) conversely described worse results in younger patients. In spite of these controversial results, the majority of authors have not found significant influence of the patient age in pain control (Aubuchon, 2010;Azar, 2009;Brisman, 2004;Dellaretti, 2008;Hayashi, 2009;Little, 2008;Longhi, 2007;Massager, 2007a;Park, 2011;Petit, 2003;Riesenburger, 2010;Rogers, 2000;Young, 1998). It seems that age is not a prognostic factor with "reasonable agreement".…”

Section: Clinical Variablesmentioning

confidence: 99%

Clinical, Anatomo-Radiological and Dosimetric Features Influencing Pain Outcome After Gamma Knife Treatment of Trigeminal Neuralgia

Lorenzoni¹,

Zarate²,

Ramón³

et al. 2011

Gamma Knife Radiosurgery

View full text Add to dashboard Cite

“…10,25 However, patients undergoing GKRS have better response rates if they have not undergone a prior surgical intervention. 23 Studies on the GKRS doses used for TN have reported that doses ≥ 70 Gy provide better pain control than doses < 70 Gy. Doses over 100 Gy are likely to result in trigeminal nerve necrosis.…”

Section: 15mentioning

confidence: 99%

A successful case of multiple stereotactic radiosurgeries for ipsilateral recurrent trigeminal neuralgia

Daugherty¹,

Bhavsar

Hahn³

et al. 2015

JNS

View full text Add to dashboard Cite

Trigeminal neuralgia is a common pain syndrome primarily managed medically, although many patients require surgical or radiotherapeutic intervention. Stereotactic radiosurgery has become a preferred method of treatment given its high efficacy rates and relatively favorable toxicity profile. However, many patients have refractory pain even after repeat courses of stereotactic radiosurgery. Historically, 2 courses have been the limit in such patients. The authors present a case of multiply recurrent trigeminal neuralgia treated with a third course of radiosurgery in which the patient had successful pain control and no additional toxicity. Meticulous attention to the therapeutic technique allows the continued application of stereotactic radiosurgery in patients.

show abstract

Radiosurgical treatment of trigeminal neuralgia: evaluating quality of life and treatment outcomes

Cited by 119 publications

References 25 publications

Gamma Knife stereotactic radiosurgical treatment of idiopathic trigeminal neuralgia: long-term outcome and complications

Gamma Knife stereotactic radiosurgical treatment of idiopathic trigeminal neuralgia: long-term outcome and complications

Clinical, Anatomo-Radiological and Dosimetric Features Influencing Pain Outcome After Gamma Knife Treatment of Trigeminal Neuralgia

A successful case of multiple stereotactic radiosurgeries for ipsilateral recurrent trigeminal neuralgia

Contact Info

Product

Resources

About