Radiotherapy After Organ-Sparing Surgery for I-Iia Stages of Left-Sided Breast Cancer

Гладилина, И. А.; Федосеенко, Д. И.; Shabanov, M; Макаров, Е. С.; Valiev, Ramiz K.; Ткаченко, Г. А.; Нечушкин, М. И.

doi:10.18027/2224-5057-2017-7-4-05-12

Cited by 3 publications

(2 citation statements)

References 11 publications

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“…Несмотря на максимальную защиту здоровых органов и тканей от поражающего воздействия ионизирующего излучения, ЛТ нередко сопровождается развитием побочных эффектов, характер и выраженность которых зависят от разовой, суммарной очаговой дозы излучения, от облучаемого объема, возраста и общего состояния пациентов, наличия у них сопутствующих заболеваний и других факторов. Так, у излеченных больных спустя 10 лет и более после ЛТ увеличивается риск радиационно-индуцированных заболеваний сердца [4].…”

Section: опухоли женской репродуктивной системы Tumors Of Female Reprunclassified

“…ЛТ на оставшуюся часть молочной железы является стандартным и обязательным компонентом органосохраняющего лечения, снижает частоту локальных рецидивов на 16 % в течение 10 лет [3,4]. Метаанализ 78 рандомизированных исследований (Early Breast Cancer Trialist's Collaborative Group, EBCTCG), включивший 42 000 пациентов с РМЖ, впервые продемонстрировал влияние локального контроля на выживаемость больных.…”

Section: Introductionunclassified

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Psychological status of patients with breast cancer following radiation therapy

Ткаченко

Гладилина

Степанова

et al. 2018

Tumors of female reproductive system

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Section: опухоли женской репродуктивной системы Tumors Of Female Reprunclassified

Section: Introductionunclassified

Psychological status of patients with breast cancer following radiation therapy

Ткаченко

Гладилина

Степанова

et al. 2018

Tumors of female reproductive system

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Skin and Subcutaneous Adipose Tissue Damage After Radiation Therapy in Breast Cancer Patients

Bazyka¹,

Litvinenko²,

Bugaytsov³

et al. 2021

Probl Radiac Med Radiobiol

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The analysis of long-term researches of the pathological changes arising in soft tissues at patients with a breast cancer as a result of radical surgical treatment and adjuvant radiotherapy is carried out in work. The article shows that the standard approach to postoperative radiation therapy, which is based only on the prevalence of the primary tumor process is not always justified. Very often it leads to excessive radiation load on the patient's body and the development of local acute and chronic radiation reactions of the skin, subcutaneous tissue and other soft tissues. In this regard, the question of differentiated purpose of radiotherapy acquires special value first of all at patients with small primary prevalence of tumor process. The paper presents the results of studies to study changes in the anterior chest wall in patients with breast cancer. In relation to the conduct of adjuvant radiotherapy more often need to use the concept of personalized radiation therapy. Radical operation, post-radiation early and late pathological changes in soft tissues, disturbance of microcirculation of lymph and blood, disturbance of innervation of vessels of an upper extremity, peripheral nerves in system of a cervical and plexus plexus, leads to intensive degenerative and dystrophic changes in soft tissues of the upper. and causes morphological changes in them and further progression of reflex neurovascular and neurodystrophic disorders. Based on the data of adverse effects of radiotherapy on the skin and surrounding tissues, as well as to reduce excessive radiation exposure to the patient's body, a differentiated approach to the appointment of adjuvant radiation therapy. The Scientific Council meeting of NAMS approved the NRCRM Annual Report. Key words: breast cancer, radiation therapy, adjuvant radiation therapy, complications of radiation therapy, radiation reactions, radiation injuries.

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Radiation-Induced Damage to the Cardiovascular System After Radiation Therapy in Women With Breast Cancer

Bazyka

Lytvynenko

Demianov

2022

Probl Radiac Med Radiobiol

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Despite current research in the development of drug-based cytostatic and targeted therapies in the treatment of breast cancer, radiation therapy (RT) is an important component in the treatment of this pathology in the postoperative period. At the same time, an important problem is the development of pathological changes in the heart in the long-term period, which worsen the quality of life and increase the risk of cardiac death 10 or more years after RT The problem of heart damage due to RT is gaining new significance due to the existing increase in the number of cancer patients requiring radiation exposure in the modern world. RT of malignant tumors of the breast and organs of the chest cavity causes damage to all structures of the heart, including the coronary arteries, valves, conducting system, pericardium. The frequency of heart damage increases in proportion to the time that has passed after RT. According to some authors, the prevalence of clinically significant radiation-induced heart diseases 5–10 years after RT is 10–30 %, and the frequency of asymptomatic lesions is 88 %. The duration of the latent period can reach 15–20 years. The work has an analysis of long-term studies of the presence of pathological changes that are found in the heart tissues of patients with breast cancer, as a result of radiation therapy. Key words: breast cancer, radiation therapy, adjuvant radiation therapy, radiation damage to the heart.

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Radiotherapy After Organ-Sparing Surgery for I-Iia Stages of Left-Sided Breast Cancer

Cited by 3 publications

References 11 publications

Psychological status of patients with breast cancer following radiation therapy

Psychological status of patients with breast cancer following radiation therapy

Skin and Subcutaneous Adipose Tissue Damage After Radiation Therapy in Breast Cancer Patients

Radiation-Induced Damage to the Cardiovascular System After Radiation Therapy in Women With Breast Cancer

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