Radiotherapy for Kimura's disease: The optimum dosage

Hareyama, Masato; Oouchi, Atsushi; Nagakura, Hisayasu; Asakura, Kohji; Saitô, Akio; Satoh, Masaaki; Tamakawa, Mitsuharu; Akiba, Hidenari; Sakata, K; Yoshida, Shigeo; Koito, Kazumitu; Imai, Kohzoh; Kataura, Akikatsu; Morita, Kazuo

doi:10.1016/s0360-3016(97)00813-4

Cited by 56 publications

(32 citation statements)

References 9 publications

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“…Second, many different regional lymph nodes (14) or extremities (15) involvement at presentation have been reported. Third, the rate of recurrence may be as high as 257 5% after surgical excision (11,16) and 11~17% after local radiotherapy (11,17 …”

Section: F I G U R E 2 ( A) P H O T O Mi C R O G R a P H O F T H E mentioning

confidence: 99%

Kimura's Disease with Generalized LymphadenopathyDemonstrated by Positron Emission Tomography Scan

et al. 2006

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Section: F I G U R E 2 ( A) P H O T O Mi C R O G R a P H O F T H E mentioning

confidence: 99%

Kimura's Disease with Generalized LymphadenopathyDemonstrated by Positron Emission Tomography Scan

et al. 2006

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“…Another study demonstrated that radiotherapy (20 -45 Gy) was more effective than local excision and steroid treatment, with local response rates of 64.3% versus 22.2%, respectively. No adverse effects were observed during a mean follow-up period of 65 months [20]. However, considering the benign nature of Kimura's disease, further investigation may be required, and caution using radiation outside of recurrent, disfiguring lesions is required.…”

Section: Discussionmentioning

confidence: 93%

Kimura’s Disease—A Rare Cause of Head and Neck Swelling

Rao¹,

Kumar²

2014

IJOHNS

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Kimura's disease (KD) is a chronic inflammatory disorder with unknown etiology, most commonly manifesting as painless unilateral cervical lymphadenopathy or subcutaneous masses in the head or neck region. The disease is characterized by a triad of painless subcutaneous masses in the head or neck region, blood and tissue eosinophilia, and markedly elevated serum immunoglobulin E levels. Kimura's disease is an unusual vascular tumor that typically occurs at 20 to 30 years of age. There has been no documented case of malignant transformation; however, recurrence rates after excision may be as high as 25%. Surgery and medical therapy are useful for treatment. We present a 14 years old male developed a unilateral cervical mass associated with KD. It was a recurrence of disease. As a complete excisional resection of the mass already done 1 year back at some other centre, we decided to give medical treatment for Kimura's disease.

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“…A dose of 5 mg/kg/day was administered for 7 days, then tapered. Radiotherapy has been used to treat recurrent or persistent lesions [13]. In summary, Kimura's disease is an indolent, benign, but locally disfiguring disease, whose true importance lies in its ability to mimic a number of other benign inflammatory and neoplastic conditions of the head and neck.…”

Section: Discussionmentioning

confidence: 99%

Kimura’s disease – a rare entity

Talwar¹,

Puri²

2013

Our Dermatol Online

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Introduction: Kimura's disease is a benign, but locally injurious disease with a marked predilection for the head and neck. Case Report: We present two cases of this rare disease. Discussion: Of uncertain aetiology, its tendency to present as a discrete, enlarging mass with associated lymphadenopathy makes it a condition of interest to clinicians who see head and neck pathology. Although rare, there are increasing numbers of reports of the condition and it should become part of the standard differential diagnosis.

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Radiotherapy for Kimura's disease: The optimum dosage

Cited by 56 publications

References 9 publications

Kimura's Disease with Generalized LymphadenopathyDemonstrated by Positron Emission Tomography Scan

Kimura's Disease with Generalized LymphadenopathyDemonstrated by Positron Emission Tomography Scan

Kimura’s Disease—A Rare Cause of Head and Neck Swelling

Kimura’s disease – a rare entity

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