Raman spectroscopic study of 6-amino-7-deazapurine

Ganbold, Erdene‐Ochir; Kang, Daeseung; Joo, Sang‐Woo

doi:10.1016/j.vibspec.2015.06.001

Cited by 7 publications

(2 citation statements)

References 23 publications

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“…Accordingly, we have examined the Raman and SERS spectra of 8AA to determine its adsorption orientation on Ag NPs. Our findings complement previous SERS studies of adenine analogues and other modified nucleobases . For assignment of vibrational modes, the 8AA Raman spectrum was simulated using density functional theory (DFT) at the B3LYP level.…”

Section: Introductionsupporting

confidence: 79%

Adsorption orientation of 8‐azaadenine on silver nanoparticles determined by SERS and DFT

Harroun

Zhang

Chen

et al. 2017

J Raman Spectroscopy

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8‐Azaadenine (8AA) is structurally similar to both adenine and benzotriazole, and therefore, it is reasonable that it could adsorb onto noble metal nanoparticles (NPs) in an orientation analogous to either one. In this study, Raman and surface‐enhanced Raman spectroscopy (SERS) of 8AA are investigated to determine its adsorption orientation on Ag NPs. In support of the analysis, the Raman spectra of 8AA and various Ag+/8AA complexes were simulated using density functional theory (DFT) at the B3LYP level. For both normal Raman and surface‐enhanced Raman spectroscopy, good agreement is observed between the experimental and simulated spectra. Our findings show that 8AA adsorbs onto Ag NPs via its N3 and N9 atoms side in an adenine‐like manner. This result may be useful for nanoparticle‐mediated drug delivery strategies of 8‐azapurines or similar molecules with biological activities.

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Section: Introductionsupporting

confidence: 79%

Adsorption orientation of 8‐azaadenine on silver nanoparticles determined by SERS and DFT

Harroun

Zhang

Chen

et al. 2017

J Raman Spectroscopy

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“…Isotopic labelling has also been used elsewhere to confirm that the intense ≈730 cm −1 Raman band commonly observed in bacteria is indeed due to adenine . Other SERS studies have investigated endocyclic chemical modifications, such as 6‐amino‐7‐deazapurine, that suggested N3 adsorption on gold, but was seemingly unsure on silver . In the case of 8‐azaadenine, a recent study compared experimental and DFT‐simulated SERS of this molecule (Figure ).…”

Section: Discussionmentioning

confidence: 99%

The Controversial Orientation of Adenine on Gold and Silver

Harroun

2018

ChemPhysChem

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In which orientation does adenine adsorb on gold and silver surfaces? This question has been a matter of debate for over 30 years. Since the dawn of surface-enhanced Raman spectroscopy (SERS); it and other techniques such as tip-enhanced Raman spectroscopy (TERS), surface-enhanced infrared absorption spectroscopy (SEIRAS), scanning tunneling microscopy (STM), density functional theory (DFT) simulations, and more, have been used in many attempts to answer this seemingly straightforward, yet controversial, question. Herein, the timeline and recent advances on this topic are explored, and the frequently contradictory findings are put into context and discussed.

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Study on the thermal decomposition of famciclovir

You

Wang

2017

J Therm Anal Calorim

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Raman spectroscopic study of 6-amino-7-deazapurine

Cited by 7 publications

References 23 publications

Adsorption orientation of 8‐azaadenine on silver nanoparticles determined by SERS and DFT

Adsorption orientation of 8‐azaadenine on silver nanoparticles determined by SERS and DFT

The Controversial Orientation of Adenine on Gold and Silver

Study on the thermal decomposition of famciclovir

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