Raman Spectroscopy of Blood and Urine Specimens

Berger, Andrew J.

doi:10.1007/978-3-642-02649-2_16

Cited by 6 publications

(2 citation statements)

References 27 publications

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“…Raman spectroscopy can also be employed to discriminate blood from other body fluids [14][15][16][17]. Quantitative analysis of analytes in blood and plasma has been carried out [19][20][21][22][23] including in vivo measurement of glucose concentration [24][25][26] and blood lactic acid concentration [27]. There have been several previous studies involving the detection of exogenous chemical composition in blood including drugs [28,29] and alcohol [30].…”

Section: Laser Physics Lettersmentioning

confidence: 99%

Non-invasive prediction of bloodstain age using the principal component and a back propagation artificial neural network

Sun¹,

Meng²,

Zhang³

et al. 2017

Laser Phys. Lett.

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The age determination of bloodstains is an important and immediate challenge for forensic science. No reliable methods are currently available for estimating the age of bloodstains. Here we report a method for determining the age of bloodstains at different storage temperatures. Bloodstains were stored at 37 °C, 25 °C, 4 °C, and −20 °C for 80 d. Bloodstains were measured using Raman spectroscopy at various time points. The principal component and a back propagation artificial neural network model were then established for estimating the age of the bloodstains. The results were ideal; the square of correlation coefficient was up to 0.99 (R 2 > 0.99) and the root mean square error of the prediction at lowest reached 55.9829 h. This method is real-time, non-invasive, non-destructive and highly efficiency. It may well prove that Raman spectroscopy is a promising tool for the estimation of the age of bloodstains.

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Section: Laser Physics Lettersmentioning

confidence: 99%

Non-invasive prediction of bloodstain age using the principal component and a back propagation artificial neural network

Sun¹,

Meng²,

Zhang³

et al. 2017

Laser Phys. Lett.

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“…Raman spectroscopy has accurately measured analytes of blood and urine samples. [ 76 ] Caspers et al . [ 11 ] have taken high-quality Raman spectra of dermal capillaries in vivo .…”

Section: Diagnosis Of Other Skin Diseasesmentioning

confidence: 99%

Raman spectroscopy: Incorporating the chemical dimension into dermatological diagnosis

Sharma

Zarrow

et al. 2016

Indian J Dermatol

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Raman spectroscopy provides chemical analysis of tissue in vivo. By measuring the inelastic interactions of light with matter, Raman spectroscopy can determine the chemical composition of a sample. Diseases that are visually difficult to visually distinguish can be delineated based on differences in chemical composition of the affected tissue. Raman spectroscopy has successfully found spectroscopic signatures for skin cancers and differentiated those of benign skin growths. With current and on-going advances in optics and computing, inexpensive and effective Raman systems may soon be available for clinical use. Raman spectroscopy provides direct analyses of skin lesions, thereby improving both disease diagnosis and management.

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Combination of prostate-specific antigen detection and micro-Raman spectroscopy for confirmatory semen detection

Feine¹,

Gafny²,

Pinkas

2017

Forensic Science International

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Raman Spectroscopy of Blood and Urine Specimens

Cited by 6 publications

References 27 publications

Non-invasive prediction of bloodstain age using the principal component and a back propagation artificial neural network

Non-invasive prediction of bloodstain age using the principal component and a back propagation artificial neural network

Raman spectroscopy: Incorporating the chemical dimension into dermatological diagnosis

Combination of prostate-specific antigen detection and micro-Raman spectroscopy for confirmatory semen detection

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