Randomized trial of progressive resistance training to counteract the myopathy of chronic heart failure

Pu, Charles T.; Johnson, Meredith T.; Forman, Daniel E.; Hausdorff, Jeffrey M.; Roubenoff, Ronenn; Foldvari, Mona; Fielding, Roger A.; Singh, Maria A. Fiatarone

doi:10.1152/jappl.2001.90.6.2341

Cited by 242 publications

(212 citation statements)

References 61 publications

Supporting

Mentioning

188

Contrasting

Unclassified

Order By: Relevance

“…In the past, PRT has been viewed as an inherently risky form of exercise and is still deliberately avoided by many clinicians in their physical activity recommendations to older adults and those with diseases such as diabetes, hypertension, and cardiovascular disease. A wealth of data demonstrates that PRT is indeed safe, effective, well accepted, and potentially more feasible than aerobic exercise in many complex patient groups including the elderly and individuals with disability or disease (32,34,42,43). More- (32).…”

Section: Prt As Treatment For Type 2 Diabetesmentioning

confidence: 99%

See 1 more Smart Citation

Battling Insulin Resistance in Elderly Obese People With Type 2 Diabetes

2003

Self Cite

View full text Add to dashboard Cite

-Exercise improves insulin resistance and has beneficial effects in preventing and treating type 2 diabetes. However, aerobic exercise is hindered in many type 2 diabetic patients because of advancing age, obesity, and other comorbid conditions. Weight lifting or progressive resistance training (PRT) offers a safe and effective exercise alternative for these people. PRT promotes favorable energy balance and reduced visceral fat deposition through enhanced basal metabolism and activity levels while counteracting age-and disease-related muscle wasting. PRT improves insulin sensitivity and glycemic control; increases muscle mass, strength, and endurance; and has positive effects on bone density, osteoarthritic symptoms, mobility impairment, self-efficacy, hypertension, and lipid profiles. PRT also alleviates symptoms of anxiety, depression, and insomnia in individuals with clinical depression and improves exercise tolerance in individuals with cardiac ischemic disease and congestive heart failure; all of these aspects are relevant to the care of diabetic elders. Moreover, PRT is safe and well accepted in many complex patient populations, including very frail elderly individuals and those with cardiovascular disease. The greater feasibility of using PRT over aerobic exercise in elderly obese type 2 diabetic individuals because of concomitant cardiovascular, arthritic, and other disease provides a solid rationale for investigating the global benefits of PRT in the management of diabetes. Diabetes Care 26:1580 -1588, 2003ADVANCING AGE AND TYPE 2 DIABETES -The value of tight blood glucose control in type 2 diabetes has been convincingly demonstrated in the U.K. Prospective Diabetes Study, among other studies. Improvement in glycemic control per se, irrespective of the means of attaining this, is the critical factor in reducing the risk of chronic diabetic complications (1). Gaining and maintaining good glycemic control hinges on enhancing insulin availability or secretion and overcoming insulin resistance. Unfortunately, advancing age, central obesity, and physical inactivity hinder medical management and may hasten development of chronic complications, particularly in elderly people who may have lived with diabetes for decades. Even when glycemic control is near optimal with medication, reducing insulin resistance by any other means must be explored in view of these adverse consequences (1).Because skeletal muscle is the biggest reservoir for glucose disposal (2), muscle wasting from aging and inactivity exacerbate problems of peripheral glucose uptake. Muscle weakness, decreased muscle mass, decreased activation of glycogen synthase, and changes in type IIb skeletal muscle fiber numbers are related to and may precede insulin resistance, glucose intolerance, and type 2 diabetes (3-5). Visceral fat deposition in older adults may be causally related to elevated cortisol secretion in response to stressors (6). Thus, decreased muscle mass, increased visceral adiposity, and the typical decline in physical activity...

show abstract

Section: Prt As Treatment For Type 2 Diabetesmentioning

confidence: 99%

“…In individuals with cardiovascular disease, PRT is well-tolerated and complementary to an aerobic training regimen (42,43). In some cases, PRT may even be preferable to an aerobic exercise regimen because of its lower HR and RPP response.…”

Section: Cardiovascular Diseasementioning

confidence: 99%

Battling Insulin Resistance in Elderly Obese People With Type 2 Diabetes

2003

Self Cite

View full text Add to dashboard Cite

show abstract

“…Resistance training has recently been recognized as a useful therapeutic tool for the treatment of a number of chronic diseases (12)(13)(14)(15)(16)(17)(18)(19) and has been demonstrated to be safe and efficacious for the elderly (20,21) and obese (22) individuals. Similar to aerobic exercise, resistance training has been reported to enhance insulin sensitivity (23)(24)(25), daily energy expenditure (26,27), and quality of life (20,28).…”

mentioning

confidence: 99%

Resistance Training and Type 2 Diabetes

2006

View full text Add to dashboard Cite

“…This training modality has been successfully used in the rehabilitation of elderly subjects and in patients with chronic heart failure to improve peripheral muscle force, exercise capacity and ambulation [12][13][14]. Resistance training enhanced peripheral muscle force, muscle endurance and whole body endurance in COPD patients, in comparison with a control group (no intervention) [7,15].…”

mentioning

confidence: 99%

Resistanceversusendurance training in patients with COPD and peripheral muscle weakness

Spruit¹,

Gosselink²,

Troosters³

et al. 2002

Eur Respir J

273

197

View full text Add to dashboard Cite

The effects of endurance training on exercise capacity and health-related quality of life (HRQL) in chronic obstructive pulmonary disease (COPD) patients have been studied thoroughly, while resistance training has been rarely evaluated. This study investigated the effects of resistance training in comparison with endurance training in patients with moderate to severe COPD and peripheral muscle weakness (isometric knee extension peak torque v75% predicted).Forty-eight patients (age 64 ¡ 8 yrs, forced expiratory volume in one second 38 ¡ 17% pred) were randomly assigned to resistance training (RT, n=24) or endurance training (ET, n=24). The former consisted of dynamic strengthening exercises. The latter consisted of walking, cycling and arm cranking. Respiratory and peripheral muscle force, exercise capacity, and HRQL were re-evaluated in all patients who completed the 12-week rehabilitation (RT n=14, ET n=16).Statistically significant increases in knee extension peak torque (RT 20¡21%, ET 42¡21%), maximal knee flexion force (RT 31¡39%, ET 28¡37%), elbow flexion force (RT 24¡19%, ET 33¡25%), 6-min walking distance (6MWD) (RT 79¡74 m, ET 95¡57 m), maximum workload (RT 15¡16 Watt, ET 14¡13 Watt) and HRQL (RT 16¡25 points, ET 16¡15 points) were observed. No significant differences in changes in HRQL and 6MWD were seen between the two treatments.Resistance training and endurance training have similar effects on peripheral muscle force, exercise capacity and health-related quality of life in chronic obstructive pulmonary disease patients with peripheral muscle weakness.

show abstract

Randomized trial of progressive resistance training to counteract the myopathy of chronic heart failure

Cited by 242 publications

References 61 publications

Battling Insulin Resistance in Elderly Obese People With Type 2 Diabetes

Battling Insulin Resistance in Elderly Obese People With Type 2 Diabetes

Resistance Training and Type 2 Diabetes

Resistanceversusendurance training in patients with COPD and peripheral muscle weakness

Contact Info

Product

Resources

About