Rapid analysis of persistent organic pollutants by solid phase microextraction in serum samples

Flores-Ramírez, Rogelio; Ortiz-Pérez, M. D.; Batres-Esquivel, Lilia E.; Castillo, Claudia G.; Ilizaliturri-Hernández, César A.; Dı́az-Barriga, Fernando

doi:10.1016/j.talanta.2014.02.023

Cited by 21 publications

(11 citation statements)

References 39 publications

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“…Flores‐Ramirez et al. studied the biomonitoring of PCBs and OCPs in children's serum ( n = 96) collected from Mexico [60]. They found relatively high concentrations of PCB congeners and OCPs in Mexican children compared to the United States, Spain, Rumania, and Germany.…”

Section: Resultsmentioning

confidence: 99%

Solid‐phase microextraction for the human biomonitoring of environmental chemicals: Current applications and future perspectives

Kim

Karthikraj

2020

J of Separation Science

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Sample preparation is one of the crucial steps in the analytical chemistry including human biomonitoring studies. Although there are several traditional approaches available, solid‐phase microextraction is emerged as one of the pioneering techniques due to its simplicity, rapidness, wide applicability, and miniaturization of traditional sample preparation (e.g., use of less or no organic solvents). There are few earlier review articles available on the advancements in solid‐phase microextraction and its use for the measurement of environmental chemicals in various types of environmental samples. However, a collective information on applicability and current usage of solid‐phase microextraction for the human biomonitoring of environmental chemicals are scarce, nonetheless, rising demands on innovative analytical approaches for human biomonitoring studies. Hence, in this review article, we covered the application of solid‐phase microextraction as extraction/purification methods for more than 15 classes of environmental chemicals to assess their respective exposure levels and associated health outcomes in various human population reported across the globe. Further, a detailed discussion on various types of matrix used, nature of coupled analytical instrumentations, and limitations and future perspectives of solid‐phase microextraction for human biomonitoring studies is presented in this review.

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Section: Resultsmentioning

confidence: 99%

Solid‐phase microextraction for the human biomonitoring of environmental chemicals: Current applications and future perspectives

Kim

Karthikraj

2020

J of Separation Science

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“…This trend is confirmed in the last lustrum since most of the published works on this topic have been directed, as well as to the assay of markers of several pathological conditions [210][211][212], toward the determination of several contaminants in urine samples [14,74,83,[213][214][215][216][217][218][219]. Few studies focused on hair [220][221][222], three papers were published about analysis in blood/serum [29,223,224], and one regarding meconium [225]. Some studies reporting the application of SPME for the analysis of urine have employed commercially available coatings such as Car/PDMS [214,216], PDMS/DVB [215], PDMS [217], and PA [14] for the extraction and further analysis of different contaminants such as VOCs [214,216], aromatic amines [215], organochlorine pesticides [217], and benzothiazoles, benzotriazoles, benzosulfonamides [14].…”

Section: The Final Endpoint: Bio-clinical Matricesmentioning

confidence: 86%

“…For this matrix, the porous structural surface together with the dual extraction mechanisms demonstrated that the SPME probe has an outstanding enrichment capacity, enhancing sensitivity by approximately 100-500 folds. In another application regarding the analysis in serum, a novel mesoporous graphitic carbon nitride@NiCo 2 O 4 nanocomposite-based fiber was prepared and used for sensitive determination of PCBs and PAHs in headspace mode [224], whereas the commercial PDMS fiber was employed in order to analyze organochlorine pesticides and PCBs levels again in headspace mode [223]. To investigate fetal exposure to volatile organic compounds, a method was developed to identify and quantify BTEX and two chlorinated solvents (trichloroethylene and tetrachloroethylene) in meconium [225].…”

Section: The Final Endpoint: Bio-clinical Matricesmentioning

confidence: 99%

Recent Applications and Newly Developed Strategies of Solid-Phase Microextraction in Contaminant Analysis: Through the Environment to Humans

Naccarato

Tagarelli

2019

Separations

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The present review aims to describe the recent and most impactful applications in pollutant analysis using solid-phase microextraction (SPME) technology in environmental, food, and bio-clinical analysis. The covered papers were published in the last 5 years (2014–2019) thus providing the reader with information about the current state-of-the-art and the future potential directions of the research in pollutant monitoring using SPME. To this end, we revised the studies focused on the investigation of persistent organic pollutants (POPs), pesticides, and emerging pollutants (EPs) including personal care products (PPCPs), in different environmental, food, and bio-clinical matrices. We especially emphasized the role that SPME is having in contaminant surveys following the path that goes from the environment to humans passing through the food web. Besides, this review covers the last technological developments encompassing the use of novel extraction coatings (e.g., metal-organic frameworks, covalent organic frameworks, PDMS-overcoated fiber), geometries (e.g., Arrow-SPME, multiple monolithic fiber-SPME), approaches (e.g., vacuum and cold fiber SPME), and on-site devices. The applications of SPME hyphenated with ambient mass spectrometry have also been described.

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“…PCB levels will be measured using gas chromatography–mass spectrometry. 18 19 In addition to total concentration, the composition of major individual congeners will also be analysed and the source of exposure inferred. The associations between congener composition and outcomes will also be analysed.…”

Section: Cohort Descriptionmentioning

confidence: 99%

Chiba study of Mother and Children's Health (C-MACH): cohort study with omics analyses

et al. 2016

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PurposeRecent epidemiological studies have shown that environmental factors during the fetal period to early childhood might affect the risk of non-communicable diseases in adulthood. This is referred to as the developmental origins of health and disease (DOHaD) concept. The Chiba study of Mother and Children's Health (C-MACH) is a birth cohort study based on the DOHaD hypothesis and involves multiomics analysis. This study aims to explore the effects of genetic and environmental factors—particularly the fetal environment and postbirth living environment—on children's health, and to identify potential biomarkers for these effects.ParticipantsThe C-MACH consists of three hospital-based cohorts. The study participants are pregnant women at <13 weeks gestation. Women who underwent an examination in one of the three hospitals received an explanation of the study. The participants consented to completing questionnaire surveys and the collection and storage of biological and house/environmental samples. Participants were provided unique study numbers. All of the data and biological specimens will be stored in the Chiba University Center for Preventive Medical Sciences and Chiba University Center for Preventive Medical Sciences BioBank, respectively.Findings to dateConsent to participate was obtained from 433 women. Of these women, 376 women completed questionnaires in the early gestational period. The mean age was 32.5 (4.4) years. The mean body mass index (BMI) was 21.1 (3.0) kg/m2. Before pregnancy, 72.3% of the women had a BMI of 18.5–24.9 kg/m2. During early pregnancy, 5.0% of the participants smoked.Future plansPrimary outcomes are allergy, obesity, endocrine and metabolic disorders, and developmental disorders. Genome-level, metabolome-level, umbilical cord DNA methylation (epigenome), gut microbiota and environmental chemical exposure variables will be evaluated. We will analyse the relationships between the outcomes and analytical variables.

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Rapid analysis of persistent organic pollutants by solid phase microextraction in serum samples

Cited by 21 publications

References 39 publications

Solid‐phase microextraction for the human biomonitoring of environmental chemicals: Current applications and future perspectives

Solid‐phase microextraction for the human biomonitoring of environmental chemicals: Current applications and future perspectives

Recent Applications and Newly Developed Strategies of Solid-Phase Microextraction in Contaminant Analysis: Through the Environment to Humans

Chiba study of Mother and Children's Health (C-MACH): cohort study with omics analyses

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