Rapid and selective deallylation of allyl ethers and esters using iodine in polyethylene glycol-400

NaOH/PEG-400: An eloquent system for the synthesis of new thienyl benzo[b]1,4-diazepines

“…Liquid polymers have emerged as an alternative green reaction media in organic synthesis. Polyethylene glycol (PEG-400) competed reactions [31][32][33][34][35] have attracted attention towards organic chemists due to their solvating ability and aptitude to act as a phase transfer catalyst, negligible vapor pressure, easy recyclability, ease of work-up, eco-friendly nature and low cost.…”

Ultrasound-promoted two-step synthesis of 3-arylselenylindoles and 3-arylthioindoles as novel combretastatin A-4 analogues

“…Allyl groups are widely used in organic synthesis as important protecting groups of alcohols due to the availability and stability of the corresponding allyl derivatives. Many methodologies have been documented in terms of deprotection of allyl ethers 30 31 32 33 . In our case, an allyl group was used as the protecting group of the 3′-phenolic hydroxyl group.…”

Halogens

“…30 Of practical use in carbohydrate and peptide syntheses, a metal-free and selective deallylation of aryl/alkyl allyl ethers and esters using I 2 in polyethylene glycol-400 under mild conditions has been reported. 31 I 2 has also been found to catalyse the oxidative amination of benzoxazole at the 2-position using secondary or primary amines in the presence of tert-butyl hydroperoxide under mild conditions. 32 The first report of metal-free direct syntheses of acetophenones from styrenes uses an elegant one-pot synthetic protocol of involving I 2 , O 2 and visible light.…”