Rapid Diagnosis of Lung Cancer from Palpable Metastases by Needle Thrust

Rohwedder, Jay J.; Handley, John A.; Kerr, David

doi:10.1378/chest.98.6.1393

Cited by 13 publications

(4 citation statements)

References 12 publications

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“…The evaluation of palpable cervical nodes is simplified with this approach, and evidence shows that simple percutaneous FNA provides reliable biopsy results in these cases [95]. Conversely, it was once believed that biopsy of impalpable cervical nodes was unnecessary [96]; however, it is now known that up to half of all cervical nodes harboring metastases in NSCLC patients may be impalpable at the time of presentation [92,97,98].…”

Section: Cervical Lymph Node Stagingmentioning

confidence: 99%

Lung cancer staging

Sihoe

Yim

2004

Journal of Surgical Research

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Section: Cervical Lymph Node Stagingmentioning

confidence: 99%

Lung cancer staging

Sihoe

Yim

2004

Journal of Surgical Research

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“…Fine-needle aspiration can be performed quickly at the bedside or as an outpatient with little morbidity and with a high sensitivity. 37…”

Section: Symptoms Signs and Laboratory Tests Indicating Extrathoracmentioning

confidence: 99%

Initial Evaluation of the Patient With Lung Cancer*

Beckles

Spiro

Colice

et al. 2003

Chest

190

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“…However, this scenario is increasingly rare with the advent of induction therapy. As a strategy for first-line surgical staging, biopsy of cervical nodes, either open [35] or by percutaneous FNA [36], was much more common several decades ago. More recently, it has been shown that up to one third of patients with mediastinal lymph node involvement will have occult metastases to the cervical N3 nodes, demonstrable at biopsy [37].…”

Section: Surgical Techniquesmentioning

confidence: 99%

The Future in Diagnosis and Staging of Lung Cancer

Catarino

Goldstraw²

2006

Respiration

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Surgical techniques remain central to the diagnosis and staging of lung cancer. Clinical situations which invoke the role of surgery include the diagnosis of solitary pulmonary masses, staging of the mediastinum, restaging of the mediastinum and the assessment of resectability. The techniques available include cervical mediastinoscopy, anterior mediastinotomy, video-assisted thoracoscopy and different procedures for intra-operative mediastinal lymph node assessment including systematic nodal dissection, lobe-specific nodal dissection and sentinel node mapping. The staging of lung cancer is continuously evolving as technological advances combine with clinical advances to better stratify patients into treatment and prognostic categories and alter pre-operative investigation algorithms. Although most of the surgical techniques have been around for many years, it is their application in future which is likely to change. The increasing use of positron emission tomography/computed tomography fusion imaging is raising the proportion of patients being shown to have additional lesions that could contraindicate surgical treatment but which require tissue confirmation to exclude a false-positive examination. Many such lesions are amenable to the expanding techniques available to the interventional endoscopist. The relationship between the surgeon and the endoscopist must become closer to ensure that the appropriate technique is used at each point in the patient’s pathway. The future of surgical techniques will be driven by: (1) developments in screening and imaging, with a likelihood that more early stage cancers will present and may be amenable to minimally invasive surgical approaches with the possibility of a role for robotics and nanotechnology; (2) improvements in neoadjuvant therapies which will demand flawless mediastinal staging and restaging; (3) advances in molecular biology which, whilst currently requiring that surgery provide samples of tumour and lymph node tissue to fully characterize the disease, do hold the promise that ever smaller amounts of tissue will be required and that eventually the genetic fingerprint will provide a biological ultrastaging to perhaps supersede anatomical staging.

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Rapid Diagnosis of Lung Cancer from Palpable Metastases by Needle Thrust

Cited by 13 publications

References 12 publications

Lung cancer staging

Lung cancer staging

Initial Evaluation of the Patient With Lung Cancer*

The Future in Diagnosis and Staging of Lung Cancer

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