ObjectiveThere is a paucity of evidence for the implementation of remote home monitoring for COVID-19 infection. The aims of this study were to: identify the key characteristics of remote home monitoring models for COVID-19 infection, explore the experiences of staff implementing these models, understand the use of data for monitoring progress against outcomes, and document variability in staffing and resource allocation.MethodsThis was a multi-site mixed methods study that combined qualitative and quantitative approaches to analyse the implementation and impact of remote home monitoring models during the first wave of the COVID-19 pandemic (March to August 2020). The study combined interviews (n=22) with staff delivering these models across eight sites in England with the collection and analysis of data on staffing models and resource allocation.ResultsThe models varied in relation to the healthcare settings and mechanisms used for patient triage, monitoring and escalation. Implementation was embedded in existing staff workloads and budgets. Good communication within clinical teams, culturally-appropriate information for patients/carers and the combination of multiple approaches for patient monitoring (app and paper-based) were considered facilitators in implementation. The mean cost per monitored patient varied from £400 to £553, depending on the model.ConclusionsIt is necessary to provide the means for evaluating the effectiveness of these models, for example, by establishing comparator data. Future research should also focus on the sustainability of the models and patient experience (considering the extent to which some of the models exacerbate existing inequalities in access to care).STRENGTHS AND LIMITATIONS OF THE STUDYThe study makes a contribution to existing evidence on remote home monitoring models by exploring the design and implementation of these models for confirmed or suspected COVID-19 cases.The study was carried out across eight remote home monitoring models implemented in England, capturing variability in the mechanisms used for triage, monitoring and escalation.Limited evidence was available to assess the effectiveness of the remote home monitoring models.No comparator data were available for the absence of remote home monitoring.The study was designed as a rapid evaluation and only captured experiences and processes of implementation in a convenience sample of eight models implemented during the first wave of the pandemic in England.