Rapid hemostasis accompanied by antibacterial action of calcium crosslinking tannic acid-coated mesoporous silica/silver Janus nanoparticles

Chen, Jiawen; Qiu, Liping; Li, Qinglin; Ai, Jian; Liu, Haiqing; Chen, Qinhui

doi:10.1016/j.msec.2021.111958

Cited by 48 publications

(15 citation statements)

References 38 publications

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“…271,324 Moreover, the significant role of TA in increasing anti-inflammatory and hemostatic activity, cellular activity, and adhesion contributes to the wound healing feature of TA-based biomaterials. 121,[325][326][327] Several studies have revealed the wound healing potential of TA-based hydrogels. Fibroblast cells cultured on an HA/TA hydrogel demonstrated a transition from spherically concentrated to polarized shape with a higher density than the pure HA hydrogel, indicating TA's positive effect on improving cell adhesion capability for HA.…”

Section: Ta-based Hydrogels In Skin Tissue Engineering and Wound Healingmentioning

confidence: 99%

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Tannic acid: a versatile polyphenol for design of biomedical hydrogels

et al. 2022

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Section: Ta-based Hydrogels In Skin Tissue Engineering and Wound Healingmentioning

confidence: 99%

Section: Ta-based Hydrogels Applications In Tissue Engineeringmentioning

confidence: 99%

Tannic acid: a versatile polyphenol for design of biomedical hydrogels

et al. 2022

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“…These released components could synergistically promote the adhesion, proliferation, migration, and angiogenetic differentiation of HUVECs at the wound sites, thereby accelerating wound healing. Following the same concepts, various types of MSNs [ 214 , 215 ], such as MSN@CS-HCA developed by Chen et al (2019) [ 216 ], tannic acid (TA)-loaded MSNs by Wang et al (2018) [ 217 ], and GQDs@HMSN(EM) by Wang et al (2020) [ 218 ], have been synthesized for a similar purpose of accelerating wound healing.…”

Section: Update On Msn Applications In Nanomedicinesmentioning

confidence: 99%

An Update on Mesoporous Silica Nanoparticle Applications in Nanomedicine

et al. 2021

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The efficient and safe delivery of therapeutic drugs, proteins, and nucleic acids are essential for meaningful therapeutic benefits. The field of nanomedicine shows promising implications in the development of therapeutics by delivering diagnostic and therapeutic compounds. Nanomedicine development has led to significant advances in the design and engineering of nanocarrier systems with supra-molecular structures. Smart mesoporous silica nanoparticles (MSNs), with excellent biocompatibility, tunable physicochemical properties, and site-specific functionalization, offer efficient and high loading capacity as well as robust and targeted delivery of a variety of payloads in a controlled fashion. Such unique nanocarriers should have great potential for challenging biomedical applications, such as tissue engineering, bioimaging techniques, stem cell research, and cancer therapies. However, in vivo applications of these nanocarriers should be further validated before clinical translation. To this end, this review begins with a brief introduction of MSNs properties, targeted drug delivery, and controlled release with a particular emphasis on their most recent diagnostic and therapeutic applications.

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“…Methods for preventing the development of the infection directly in the area of surgical intervention are being continuously improved. Although the method of vacuum therapy of wounds plays a special role, including the use of combined antibacterial drugs (primarily in the treatment of postoperative wounds with a high risk of developing a surgical infection [ 1 , 2 , 3 , 4 ]), one of the most significant areas of prevention of wound suppuration is the use of formulations based on silver, for example, in the form of nanoparticles [ 5 , 6 , 7 ]. It should be taken into account that the properties of the obtained nanoparticles will largely change depending on the conditions of their synthesis, physicochemical properties of reducing agents and stabilizers [ 8 , 9 , 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Changes in Number and Antibacterial Activity of Silver Nanoparticles on the Surface of Suture Materials during Cyclic Freezing

et al. 2022

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This article presents the results of the 10-fold cyclic freezing (−37.0 °C) and thawing (0.0 °C) effect on the number and size range of silver nanoparticles (AgNPs). AgNPs were obtained by the cavitation-diffusion photochemical reduction method and their sorption on the fiber surface of various suture materials, perlon, silk, and catgut, was studied. The distribution of nanoparticles of different diameters before and after the application of the cyclic freezing/thawing processes for each type of fibers studied was determined using electron microscopy. In general, the present study demonstrates the effectiveness of using the technique of 10-fold cyclic freezing. It is applicable to increase the absolute amount of AgNPs on the surface of the suture material with a simultaneous decrease in the size dispersion. It was also found that the application of the developed technique leads to the overwhelming predominance of nanoparticles with 1 to 15 nm diameter on all the investigated fibers. In addition, it was shown that after the application of the freeze/thaw method, the antibacterial activity of silk and catgut suture materials with AgNPs was significantly higher than before their treatment by cyclic freezing.

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Rapid hemostasis accompanied by antibacterial action of calcium crosslinking tannic acid-coated mesoporous silica/silver Janus nanoparticles

Cited by 48 publications

References 38 publications

Tannic acid: a versatile polyphenol for design of biomedical hydrogels

Tannic acid: a versatile polyphenol for design of biomedical hydrogels

An Update on Mesoporous Silica Nanoparticle Applications in Nanomedicine

Changes in Number and Antibacterial Activity of Silver Nanoparticles on the Surface of Suture Materials during Cyclic Freezing

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